[HTML][HTML] Towards a re-emergence of chloroquine sensitivity in Côte d'Ivoire?
Abstract Background Resistance of Plasmodium falciparum to anti-malarial drugs has
hampered efforts to eradicate malaria. Recent reports of a decline in the prevalence of …
hampered efforts to eradicate malaria. Recent reports of a decline in the prevalence of …
[HTML][HTML] Use of proscribed chloroquine is associated with an increased risk of pfcrt T76 mutation in some parts of Ghana
Background After years of disuse of chloroquine (CQ) as first-line anti-malarial drug in
Ghana, reports from molecular studies conducted in parts of the country indicate varying …
Ghana, reports from molecular studies conducted in parts of the country indicate varying …
[HTML][HTML] Chloroquine sensitivity: diminished prevalence of chloroquine-resistant gene marker pfcrt-76 13 years after cessation of chloroquine use in Msambweni …
WC Kiarie, L Wangai, E Agola, FT Kimani, C Hungu - Malaria journal, 2015 - Springer
Background Plasmodium falciparum resistance to chloroquine (CQ) denied healthcare
providers access to a cheap and effective anti-malarial drug. Resistance has been proven to …
providers access to a cheap and effective anti-malarial drug. Resistance has been proven to …
In vivo chloroquine resistance and prevalence of the pfcrt codon 76 mutation in Plasmodium falciparum isolates from the Republic of Congo
PI Mayengue, M Ndounga, MM Davy, N Tandou… - Acta Tropica, 2005 - Elsevier
Chloroquine (CQ) resistance in Plasmodium falciparum has been particularly associated
with mutations in the pfcrt gene. The present study was carried out in the malaria …
with mutations in the pfcrt gene. The present study was carried out in the malaria …
[HTML][HTML] Assessment of the molecular marker of Plasmodium falciparum chloroquine resistance (Pfcrt) in Senegal after several years of chloroquine withdrawal
M Ndiaye, B Faye, R Tine, JL Ndiaye, A Lo… - The American journal …, 2012 - ncbi.nlm.nih.gov
As a result of widespread antimalarial drug resistance, all African countries with endemic
malaria have, in recent years, changed their malaria treatment policy. In Senegal, the health …
malaria have, in recent years, changed their malaria treatment policy. In Senegal, the health …
[HTML][HTML] Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania
A Mohammed, A Ndaro, A Kalinga, A Manjurano… - Malaria journal, 2013 - Springer
Background Plasmodium falciparum resistance to anti-malarial drugs remains a major
obstacle to the control of malaria. In 2001 Tanzania replaced chloroquine (CQ) with …
obstacle to the control of malaria. In 2001 Tanzania replaced chloroquine (CQ) with …
[HTML][HTML] Lack of significant recovery of chloroquine sensitivity in Plasmodium falciparum parasites following discontinuance of chloroquine use in Papua New Guinea
M Sekihara, SI Tachibana, M Yamauchi, S Yatsushiro… - Malaria Journal, 2018 - Springer
Abstract Background Chloroquine treatment for Plasmodium falciparum has been
discontinued in almost all endemic regions due to the spread of resistant isolates. Reversal …
discontinued in almost all endemic regions due to the spread of resistant isolates. Reversal …
[HTML][HTML] A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine …
M Frank, N Lehners, PI Mayengue, J Gabor… - Malaria Journal, 2011 - Springer
Background Chloroquine resistance (CR) decreased after the removal of chloroquine from
national treatment guidelines in Malawi, Kenia and Tanzania. In this investigation the …
national treatment guidelines in Malawi, Kenia and Tanzania. In this investigation the …
[HTML][HTML] Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt
N Takahashi, K Tanabe, T Tsukahara, M Dzodzomenyo… - Malaria journal, 2012 - Springer
Abstract Background In Plasmodium falciparum, resistance to chloroquine (CQ) is conferred
by a K to T mutation at amino acid position 76 (K76T) in the P. falciparum CQ transporter …
by a K to T mutation at amino acid position 76 (K76T) in the P. falciparum CQ transporter …
The T76 mutation in the pfcrt gene of Plasmodium falciparum and clinical chloroquine resistance phenotypes in Papua, Indonesia
JD Maguire, AI Susanti, Krisin, P Sismadi… - Annals of Tropical …, 2001 - Taylor & Francis
The T76 mutation in the pfcrt gene has been linked to chloroquine (CQ) resistance in
Plasmodium falciparum. PCR-based analysis of pfcrt alleles was performed on pre …
Plasmodium falciparum. PCR-based analysis of pfcrt alleles was performed on pre …