The autologous mixed-lymphocyte reaction

ME Weksler, CE Moody Jr, RW Kozak - Advances in immunology, 1981 - Elsevier
Publisher Summary It had been suggested that the autologous mixed-lymphocyte reaction
(MLR) might result from perturbations of the responding or stimulating cells during cell …

Autologous mixed lymphocyte reaction in health and disease states in man

S Gupta - Vox Sanguinis, 1983 - karger.com
In this review are discussed the nature of T cell subsets, defined with monoclonal antibodies,
responding in T-non-T and TT autologous mixed-lymphocyte reactions (AMLR) and antigens …

Human mixed-lymphocyte culture reaction: genetics, specificity, and biological implications

B Dupont, JA Hansen, EJ Yunis - Advances in immunology, 1976 - Elsevier
Publisher Summary This chapter deals with the new and exciting developments in MLC
(multi-level cell) typing in human histocompatibility studies. The genetics, specificity, and …

Importance of HLA‐D antigens for the cooperation between human monocytes and T lymphocytes

GS Hansen, B Rubin, SF Sørensen… - European Journal of …, 1978 - Wiley Online Library
The ability of autologous and allogeneic monocytes to restore the responsiveness of purified
T lymphocytes to tuberculin (PPD) was studied in twelve different experiments involving …

Immunoglobulin secretion in the human autologous mixed leukocyte reaction. Definition of a suppressor-amplifier circuit using monoclonal antibodies.

PA Gatenby, BL Kotzin, GS Kansas… - The Journal of …, 1982 - rupress.org
The induction of immunoglobulin (Ig) synthesis in the autologous MLR has an absolute
requirement for helper/inducer (Leu-3) T cells, whereas an excess of suppressor/cytotoxic …

Specific positive selection of lymphocytes reactive to strong histocompatibility antigens

JC Howard, DB Wilson - The Journal of Experimental Medicine, 1974 - rupress.org
Selected populations of thymus-derived (T) rat lymphocytes having specific immunological
reactivity to chosen histocompatibility (H) alloantigens are found among the cellular products …

Serologically defined and lymphocyte-defined components of the major histocompatibility complex in the mouse

FH Bach, MB Widmer, ML Bach, J Klein - The Journal of Experimental …, 1972 - rupress.org
The mixed leukocyte culture (MLC) test is an in vitro model of the recognition phase of the
homograft response. For the most part, activation in MLC is dependent on differences of the …

Immunoregulatory function of T cells activated in the autologous mixed lymphocyte reaction.

SP James, GG Yenokida, AS Graeff… - … (Baltimore, Md.: 1950 …, 1981 - journals.aai.org
This study was undertaken to define the functional properties of T cells stimulated in the
autologous mixed lymphocyte reaction (MLR) by purified B cells or macrophages. In …

Failure of autologous mixed lymphocyte reactions between T and non-T cells in patients with systemic lupus erythematosus.

T Sakane, AD Steinberg… - Proceedings of the …, 1978 - National Acad Sciences
Normal human T cells proliferate vigorously when stimulated with autologous non-T cells.
This autologous mixed lymphocyte reaction (MLR) between T and non-T cells was defective …

Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules

LH Glimcher, DL Longo, I Green… - The Journal of …, 1981 - rupress.org
A system has been described that produces a murine syngeneic mixed lymphocyte
response (MLR) comparable in magnitude to an allogeneic MLR. The responder cells in …