Interleukin-10 and interferon gamma gene polymorphisms and hepatitis C virus–related liver cirrhosis risk

A Sheneef, MM Esmat, AN Mohammad… - Journal of Interferon & …, 2017 - liebertpub.com
The aim of the study was to evaluate the association between the gene polymorphisms in
interleukin-10 (IL-10) and interferon gamma (IFN-γ) genes with susceptibility and severity of …

Combined analysis of interferon-γ and interleukin-10 gene polymorphisms and chronic hepatitis C severity

N Bouzgarrou, E Hassen, K Farhat, O Bahri… - Human immunology, 2009 - Elsevier
Today there is increasing evidence concerning the contribution of pro-/anti-inflammatory
cytokine balance and genetic factors in hepatitis C pathogenesis and interindividual …

The Impact of Interferon-γ (IFN-γ) and IFN-γ-Inducible Protein 10 (IP-10) Genes' Polymorphism on Risk of Hepatitis C Virus–Related Liver Cirrhosis

RM Talaat, S Elsharnoby, MS Abdelkhalek… - Immunological …, 2022 - Taylor & Francis
Background Today there is increasing evidence concerning the association between
individual genetic polymorphisms within proinflammatory cytokines and chronic hepatitis C …

Combined effect of pro-and anti-inflammatory cytokine gene polymorphisms on susceptibility to liver cirrhosis in Tunisian HCV-infected patients

N Bouzgarrou, E Hassen, O Bahri, S Gabbouj… - Hepatology …, 2011 - Springer
Purpose Chronic hepatitis C progression is commonly attributed to the continuous activation
of the immune response with an increased production of pro-inflammatory cytokines, leading …

Association of interleukin-4 (-590 C/T) and interleukin-6 (-174 G/C) polymorphism in pathogenesis and prognosis of hepatitis C virus infection

Y Badshah, N Arshad, M Khan, A Jannat… - Journal of Interferon & …, 2018 - liebertpub.com
Progression of hepatitis C virus (HCV) infection is facilitated by an intricate cellular network
comprising host genetics and viral factors. Interleukin (IL)-4 and IL-6 are the components of …

Impact of interleukin IL-6 rs-1474347 and IL-10 rs-1800896 genetic polymorphisms on the susceptibility of HCV-infected Egyptian patients to hepatocellular carcinoma

RM Abd El-Baky, HF Hetta, G Koneru, M Ammar… - Immunologic …, 2020 - Springer
Hepatitis C virus (HCV) is considered leading cause of cirrhosis and hepatocellular
carcinoma (HCC). We aimed to examine the association of IL-6 and IL-10 single-nucleotide …

Cytokine gene polymorphisms and the susceptibility to liver cirrhosis in patients with chronic hepatitis C

MJ Bahr, M El Menuawy, KHW Boeker… - Liver …, 2003 - Wiley Online Library
Background: The speed of fibrosis progression varies considerably between patients with
chronic hepatitis C. This study analyzed whether cytokine gene polymorphisms are …

Interleukin-10 gene polymorphisms in association with susceptibility to chronic hepatitis C virus infection: a meta-analysis study

LZ Zhang, TC Zhang, FM Pan, ZH Zhang, X Li - Archives of virology, 2010 - Springer
A relationship between chronic hepatitis C virus (HCV) infection and interleukin-10 (IL-10)
gene polymorphisms has been reported with controversial results in different studies. In an …

Haplotype analysis of interleukin-10 gene promoter polymorphisms in chronic hepatitis C infection: a case control study

S Sepahi, A Pasdar, M Ahadi, S Gerayli… - Viral …, 2014 - liebertpub.com
High prevalence of hepatitis c virus (HCV) infection in some areas necessitates more
investigations of the causative factors. Genetic factors that cause disruption in operation or …

Impact of IL-10 (-1082) promoter–single nucleotide polymorphism on the outcome of hepatitis C virus genotype 4 infection

SF Helal, HE Gomaa, EH Thabet… - Clinical Medicine …, 2014 - journals.sagepub.com
Immuneregulatory cytokines may influence the hepatitis C virus (HCV) infection outcome.
This study aimed to determine the genotypic and allelic frequencies of the interleukin (IL)-10 …