High-dose hydroxyurea plus G-CSF mobilize BCR-ABL-negative progenitor cells (CFC, LTC-IC) into the blood of newly diagnosed CML patients at any time of …

AL Petzer, E Hochenburger, M Haun… - … of Hematotherapy & …, 2002 - liebertpub.com
The objective of this study was to analyze the mobilization kinetics of normal (BCR-ABLneg)
and malignant (BCR-ABLpos) progenitor cells using a new, low toxic, out-patient-based …

High dose hydroxyurea in collection of Philadelphia chromosome-negative stem cells in chronic myeloid leukaemia

BJ Kuss, RE Sage, KM Shepherd… - Leukemia & …, 1993 - Taylor & Francis
High dose hydroxyurea (HU) was used in a pilot study to assess its efficacy in mobilizing
Philadelphia (Ph) chromosome negative progenitor cells in chronic myeloid leukaemia …

Mobilization of Philadelphia‐negative peripheral blood mononuclear cells in chronic myeloid leukaemia using hydroxyurea and G‐CSF (filgrastim)

RJ Johnson, RG Owen, JA Child… - British journal of …, 1996 - Wiley Online Library
A relatively simple and non‐toxic out‐patient‐based regimen for the mobilization of
Philadelphia‐negative (Ph− ve) mononuclear cells in chronic myeloid leukaemia (CML) was …

Successful mobilization of Ph-negative blood stem cells with intensive chemotherapy+ G-CSF in patients with chronic myelogenous leukemia in first chronic phase

U Olsson-Strömberg, M Höglund… - Leukemia & …, 2006 - Taylor & Francis
The aim of the study was to investigate the feasibility of mobilizing Philadelphia
chromosome negative (Ph−) blood stem cells (BSC) with intensive chemotherapy and …

Mobilization and transplantation of Philadelphia chromosome‐negative peripheral blood progenitor cells in patients with CML

CF Waller, M Heinzinger, A Rosenstiel… - British journal of …, 1998 - Wiley Online Library
Mobilization and transplantation of peripheral blood progenitor cells (PBPCs) was
investigated in patients with stage IA or stage IIA chronic myelogenous leukaemia (CML) …

High-dose hydroxyurea and G-CSF to collect Philadelphia-negative cells in chronic myeloid leukemia: preliminary results

J Mehta, R Powles, S Singhal, GJ Swansbury… - Leukemia & …, 1996 - Taylor & Francis
Five patients with Ph+ chronic myeloid leukemia and no detectable diploid cells in the
marrow received 6 g hydroxyurea twice daily for 7 days followed by G-CSF to harvest Ph …

Mobilisation and reinfusion of Philadelphia negative peripheral blood mononuclear cells in chronic myeloid leukaemia with hydroxyurea and G-CSF

RJ Johnson, GM Smith - Leukemia & lymphoma, 1997 - Taylor & Francis
Unmanipulated autologous transplantation of marrow orperipheral blood stem cells has
been performed in small numbers of patients with CML for many years. More recently there …

IN VIVO MOBILIZATION OF KARYOTyPICALLY NORMAL PERIPHERAL BLOOD PROGENITOR CELLS IN HIGH‐RISK MDS, SECONDARY OR THERAPY …

AM Carella, A Dejana, E Lerma… - British journal of …, 1996 - Wiley Online Library
We have previously reported that mobilization of Philadelphia (Ph) chromosome‐negative
progenitors is possible in a significant number of Ph1‐positive acute lymphoblastic …

Mobilization of predominantly Philadelphia chromosome‐negative blood progenitors using cyclophosphamide and rHUG‐CSF in early chronic‐phase chronic myeloid …

TP Hughes, A Grigg, J Szer, J Ho, D Ma… - British journal of …, 1997 - Wiley Online Library
Mobilization of Philadelphia chromosome (Ph) negative blood progenitors was attempted in
23 newly diagnosed chronic myeloid leukaemia (CML) patients using a regimen of …

Peripheral blood stem cell mobilization by chemotherapy with and without recombinant human granulocyte colony-stimulating factor

LEES SCHWARTZBERG, R BIRCH… - Journal of …, 1992 - liebertpub.com
Chemotherapy can serve as a stimulus for mobilizing hematopoietic progenitor cells to the
peripheral blood for harvest via leukapheresis. Mobilized peripheral blood stem cells …