Uremic toxins can induce endothelial dysfunction in patients with chronic kidney disease
(CKD). Indeed, the structure of the endothelial monolayer is damaged in CKD, and studies …

Patients with chronic kidney disease (CKD) are at a highly increased risk of cardiovascular
complications, with increased vascular inflammation, accelerated atherogenesis and …

Chronic kidney disease is linked to systemic inflammation and to an increased risk of
ischemic heart disease and atherosclerosis. Endothelial dysfunction associates with …

It is obvious that retention of uremic toxins leads to endothelial dysfunction, which in turn
initiates proliferation of vascular smooth muscle cells. Yet, the entity of the cascade of …

Chronic kidney disease (CKD) is a progressive loss of renal function. The gradual decline in
kidney function leads to an accumulation of toxins normally cleared by the kidneys, resulting …

Background Cardiovascular disease is the leading cause of mortality in hemodialysis
patients and is associated with chronic inflammation. Elevation of uremic toxins, particular …

Chronic kidney disease (CKD) is associated with high mortality rates, mainly due to
cardiovascular diseases (CVD). Uremia has been considered a relevant risk factor for CVD …

Endothelial microparticles (EMPs) are vesicles derived from cell membranes, which contain
outsourced phosphatidylserine and express adhesion molecules, such as cadherin …

Patients with chronic kidney disease (CKD) have an elevated prevalence of atheromatous
(ATH) and/or non-atheromatous (non-ATH) cardiovascular disease (CVD) due to an array of …

Background: Retention of uremic toxins in patients with chronic kidney disease (CKD)
negatively affects multiple organ systems, including the cardiovascular system, resulting in …