Recent progress in research on mechanisms of action of natural products against Alzheimer's disease: Dietary plant polyphenols

Y Wang, K Wang, J Yan, Q Zhou, X Wang - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is an incurable degenerative disease of the central nervous
system and the most common type of dementia in the elderly. Despite years of extensive …

Dietary polyphenols as therapeutic intervention for Alzheimer's disease: a mechanistic insight

SNA Bukhari - Antioxidants, 2022 - mdpi.com
Dietary polyphenols encompass a diverse range of secondary metabolites found in nature,
such as fruits, vegetables, herbal teas, wine, and cocoa products, etc. Structurally, they are …

The protective role of plant biophenols in mechanisms of Alzheimer's disease

SH Omar, CJ Scott, AS Hamlin, HK Obied - The Journal of nutritional …, 2017 - Elsevier
Self-assembly of amyloid beta peptide (Aβ) into the neurotoxic oligomers followed by fibrillar
aggregates is a defining characteristic of Alzheimer's disease (AD). Several lines of …

Dietary polyphenols: A multifactorial strategy to target Alzheimer's disease

S Dhakal, N Kushairi, CW Phan, B Adhikari… - International journal of …, 2019 - mdpi.com
Ageing is an inevitable fundamental process for people and is their greatest risk factor for
neurodegenerative disease. The ageing processes bring changes in cells that can drive the …

Dietary polyphenols for treatment of Alzheimer's disease–future research and development

D Sheeja Malar, K Pandima Devi - Current Pharmaceutical …, 2014 - ingentaconnect.com
Polyphenols are the most abundant components of our daily food, occupying the major
portion of naturally occurring phytochemicals in plants. Currently, polyphenols have …

Multi-target mechanisms of phytochemicals in Alzheimer's disease: Effects on oxidative stress, neuroinflammation and protein aggregation

J Sharifi-Rad, S Rapposelli, S Sestito… - Journal of Personalized …, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a tangle-shaped
accumulation of beta-amyloid peptide fragments and Tau protein in brain neurons. The …

Protective effects of flavonoids against Alzheimer's disease: pathological hypothesis, potential targets, and structure–activity relationship

J Li, M Sun, X Cui, C Li - International Journal of Molecular Sciences, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease with high morbidity and mortality,
for which there is no available cure. Currently, it is generally believed that AD is a disease …

A systematic review on the role of natural products in modulating the pathways in Alzheimer's disease

ST Auti, YA Kulkarni - Int. J. Vitam. Nutr. Res, 2017 - econtent.hogrefe.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder to date, with no
cure or preventive therapy. Histopathological hallmarks of AD include deposition of β …

Potential therapeutic natural compounds for the treatment of Alzheimer's disease

Q Huang, W Wu, Y Wen, S Lu, C Zhao - Phytomedicine, 2024 - Elsevier
Background Alzheimer's disease (AD) is a complicated neurodegenerative disease with
cognitive impairment occurring in the older people, in which extracellular accumulation of β …

Antioxidant properties of natural polyphenols and their therapeutic potentials for Alzheimer's disease

DY Choi, YJ Lee, JT Hong, HJ Lee - Brain research bulletin, 2012 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease and most
common cause of dementia. However, there is no known way to halt or cure the …