Background: Several cross-sectional studies report brain structure differences between
healthy volunteers and subjects at genetic or clinical high risk of developing schizophrenia …

Abstract Background Psychotic experiences (PEs) are considered part of an extended
psychosis phenotype and are associated with an elevated risk of developing a psychotic …

Objectives: The aim of the present study was to use a voxel-based magnetic resonance
imaging method to investigate the neuroanatomical characteristics in subjects at high risk of …

Importance The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled
neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological …

OBJECTIVES: In early stage psychosis research the identification of neurobiological
correlates of vulnerability to schizophrenia is an important hurdle. METHODS: We …

BACKGROUND: Schizophrenia and related psychoses are associated with brain structural
abnormalities. Recent findings in 'at risk'populations have identified progressive changes in …

Computational brain-imaging studies of individuals at familial high risk for psychosis have
provided interesting results, but interpreting these findings can be a challenge due to a …

Early intervention research in schizophrenia has suggested that brain structural alterations
might be present in subjects at high risk of developing psychosis. The heterogeneity of …

Research on neurobiological impairments in clinical and genetic high risk for developing
psychosis individuals (CHR) has identified several brain abnormalities that impact both …

Neuroimaging findings in people at either genetic risk or at clinical high-risk for psychosis
(CHR-P) or bipolar disorder (CHR-B) remain unclear. A meta-analytic review of whole-brain …