Abstract Purpose Early-onset Alzheimer's disease (EOAD) and late-onset Alzheimer's
disease (LOAD) differ in neuropathological burden and type of cognitive deficits. Assessing …

Purpose We aimed to investigate associations between tau pathology and relative cerebral
blood flow (rCBF), and their relationship with cognition in Alzheimer's disease (AD), by using …

Purpose Tau pathology is associated with concurrent atrophy and decreased cerebral blood
flow (CBF) in Alzheimer's disease (AD), but less is known about their temporal relationships …

Alzheimer's disease (AD) is associated with reduced temporo-parietal cerebral blood flow
(CBF). However, a substantial variability in CBF across the clinical spectrum of AD has been …

Purpose The role of cerebral blood flow (CBF) in the early stages of Alzheimer's disease is
complex and largely unknown. We investigated cross-sectional and longitudinal …

In this issue, an article by Tiepolt et al. shows that PET scanning using [11 C] PiB can
demonstrate both cerebral blood flow (CBF) changes and amyloid-β (Aβ) deposition in …

Objective To examine the independent and interactive influences of neuroimaging
biomarkers on retrospective cognitive decline. Methods A total of 152 middle-aged and older …

Purpose Using PET imaging in a group of patients with Alzheimer's disease (AD), we
investigated whether level of education, a proxy for resilience, mitigates the harmful impact …

Introduction Dual-biomarker positron emission tomography (PET), providing complementary
information on cerebral blood flow and amyloid-β deposition, is of clinical interest for …

Abstract INTRODUCTION The “A/T/N”(amyloid/tau/neurodegeneration) framework provides
a biological basis for Alzheimer's disease (AD) diagnosis and can encompass additional …