Long non-coding RNA ZFY-AS1 represses periodontitis tissue inflammation and oxidative damage via modulating microRNA-129-5p/DEAD-Box helicase 3 X-linked …

L Cheng, YL Fan, J Cheng, J Wang, Q Liu… - …, 2022 - Taylor & Francis
ABSTRACT A large number of studies have manifested long non-coding RNA (lncRNA) is
involved in the modulation of the development of periodontitis, but the specific mechanism …

Abnormal expression of long noncoding RNA FGD5-AS1 affects the development of periodontitis through regulating miR-142-3p/SOCS6/NF-κB pathway

H Chen, Z Lan, Q Li, Y Li - Artificial Cells, Nanomedicine, and …, 2019 - Taylor & Francis
Periodontitis refers to the inflammation of gums and the surrounding structures and caused
by a bacterial infection. The infection occurs owing to poor oral hygiene and could destroy …

MicroRNA-543-3p down-regulates inflammation and inhibits periodontitis through KLF6

W Li, J Wang, W Hao, C Yu - Bioscience Reports, 2021 - portlandpress.com
Abstract MicroRNA-543-3p (miR-543-3p) has been reported to be involved in many human
disease's progression, but its role in inflammation is still unclear. After bacterial infection …

Long noncoding RNA distal-less homeobox 2 antisense 1 restrains inflammatory response and apoptosis of periodontal ligament cells by binding with microRNA-330 …

Z Wang, D Wang, S Guo, Q Zhuo, D Jiang, Z Yu - Archives of Oral Biology, 2022 - Elsevier
Objective This study aims to investigate the role of long noncoding RNA distal-less
homeobox 2 antisense 1 (DLX2-AS1) in lipopolysaccharide-induced inflammatory response …

Long non‐coding RNA 01126 promotes periodontitis pathogenesis of human periodontal ligament cells via miR‐518a‐5p/HIF‐1α/MAPK pathway

M Zhou, H Hu, Y Han, J Li, Y Zhang, S Tang… - Cell …, 2021 - Wiley Online Library
Background Periodontitis is a prevalent oral inflammatory disease, which can cause
periodontal ligament to a local hypoxia environment. However, the mechanism of hypoxia …

[HTML][HTML] DUXAP8 Promotes LPS-induced cell injury in pulpitis by regulating miR-18b-5p/HIF3A

Y Dai, G Xuan, M Yin - international dental journal, 2023 - Elsevier
Background The dysregulated long noncoding RNAs (lncRNAs) are implicated in
progression of various diseases, including pulpitis. Double homeobox A pseudogene 8 …

[HTML][HTML] Maternally-expressed gene 3 (meg3)/mir-143-3p regulates injury to periodontal ligament cells by mediating the akt/inhibitory κb kinase (ikk) pathway

Y Dong, S Feng, F Dong - Medical Science Monitor: International …, 2020 - ncbi.nlm.nih.gov
Background Dysregulated long noncoding RNAs (lncRNAs) are implicated in periodontitis
development. Nevertheless, the role and mechanism of lncRNA maternally-expressed gene …

[HTML][HTML] Long noncoding RNA related to periodontitis interacts with miR-182 to upregulate osteogenic differentiation in periodontal mesenchymal stem cells of …

L Wang, F Wu, Y Song, X Li, Q Wu, Y Duan, Z Jin - Cell death & disease, 2016 - nature.com
Periodontitis impairs the osteogenic differentiation of human periodontal mesenchymal stem
cells (hPDLSCs), but the underlying molecular mechanisms are still poorly understood …

Identification of novel key lncRNAs involved in periodontitis by weighted gene co‐expression network analysis

SH Jin, RH Zhou, XY Guan, JG Zhou… - Journal of Periodontal …, 2020 - Wiley Online Library
Abstract Background and Objective Periodontitis is a multifactorial disease that can lead to
the progressive destruction of dental support tissue. However, the detailed mechanisms and …

LncRNA MAFG‐AS1 regulates human periodontal ligament stem cell proliferation and Toll‐like receptor 4 expression

K Wangzhou, L Gong, C Liu, Y Tan, J Chen, C Li… - Oral …, 2020 - Wiley Online Library
LncRNA MAFG‐AS1 is predicted to interact with miR‐146a, which can target Toll‐like
receptor 4 (TLR4), a key player in periodontitis. This study aimed to investigate the roles of …