The E3 ubiquitin ligase MuRF1/TRIM63 was identified 20 years ago and suspected to play
important roles during skeletal muscle atrophy. Since then, numerous studies have been …

Progressive muscle wasting, also known as myopathy or muscle atrophy is a debilitating
and life-threatening disorder. Myopathy is a pathological condition of many diseases …

Abstract Background Muscle ring finger 1 (MuRF1) is a muscle‐specific ubiquitin E3 ligase
activated during clinical conditions associated with skeletal muscle wasting. Yet, there …

MuRF1 is a member of the TRIM/RBCC superfamily, a gene family that encompasses a
large variety of proteins, all sharing the conserved TRIM (Tripartite Motive) sequential array …

Abstract MuRF1 (TRIM63) is a muscle-specific E3 ubiquitin ligase and component of the
ubiquitin proteasome system. MuRF1 is transcriptionally upregulated under conditions that …

The striated muscle-specific tripartite motif (TRIM) proteins TRIM63/MURF1, TRIM55/MURF2
and TRIM54/MURF3 can function as E3 ubiquitin ligases in ubiquitin-mediated muscle …

MURF-1, MURF-2 and MURF-3 are a specific class of RING finger proteins that are
expressed in striated muscle tissues. MURF-1 has been suggested to act as an ubiquitin …

Muscle-specific RING finger protein 1 (MuRF1) is a sarcomere-associated protein that is
restricted to cardiac and skeletal muscle. In skeletal muscle, MuRF1 is up-regulated by …

The striated muscle-specific tripartite motif (TRIM) proteins TRIM63/MURF1, TRIM55/MURF2
and TRIM54/MURF3 can function as ubiquitin E3 ligases in ubiquitin-mediated muscle …

Muscle RING finger 1 (MuRF1) and muscle atrophy F-box (MAFbx)/atrogin-1 were identified
more than 10 years ago as two muscle-specific E3 ubiquitin ligases that are increased …