Objective Neuroimaging and genetic testing have been proposed for diagnostic evaluation
of infantile spasms (IS), establishing etiology in~ 60% of multicenter IS cohorts. A …

This study explores the etiology and lead time to treatment for infantile spasm (IS) patients
and their effect on treatment responsiveness, in a limited resource setting. Patients with IS …

The diagnosis, evaluation, and management of infantile spasms (IS) continue to pose
significant challenges to the treating physician. Although an evidence‐based practice …

Summary Purpose: Prior to the United Kingdom Infantile Spasms Study (UKISS), our
practice was to initiate vigabatrin for infantile spasms. However, since then we tend to use …

Studies have suggested disparate variables affecting long-term outcomes in patients with
infantile spasms. Using a retrospective chart review, the authors identified 109 patients who …

Objective Infantile spasms (IS) represent a severe epileptic encephalopathy presenting in
the first 2 years of life. Recommended first‐line therapies (hormonal therapy or vigabatrin) …

Background: We studied the clinical, neuroradiological and EEG characteristics of patients
with infantile spasms (IS) who showed focal features to reveal their long-term prognoses and …

Aim To identify the aetiology of patients with infantile spasms and propose practical
guidelines for diagnostic strategies. Method We performed a retrospective study of children …

Objective Infantile spasms are seizures associated with a severe epileptic encephalopathy
presenting in the first 2 years of life, and optimal treatment continues to be debated. This …

Background The aims of this systematic review and meta-analysis were to assess (i)
estimates of good neurodevelopmental outcome in infantile spasms (IS),(ii) if …