Simple Summary A subgroup of cancers that arises in the zone of the head and neck
(HNCs) are caused by some types of human papillomavirus (HPV), so called high-risk (HR) …

Epidemiological surveys and molecular studies have indicated that infection of human
papillomavirus (HPV) itself is necessary but insufficient for completing transformation of the …

Abstract Infection with Human papillomaviruses (HPVs) leads to the development of a wide-
range of cancers, accounting for 5% of all human cancers. A prominent example is cervical …

The aim of this review is to summarize current available information about the role of
PI3K/AKT/mTOR signaling in head and neck cancer as a potential target for new therapy …

The latest advances in the sequencing methods in head and neck squamous cell carcinoma
(HNSCC) tissues have revolutionized our understanding of the disease by taking off the veil …

Purpose: The incidence of head and neck squamous cell carcinomas (HNSCC) associated
with human papillomavirus (HPV) infection has increased over the past decades in the …

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease arising
from the mucosal epithelia in the head and neck region. The most common risk factors are …

Activation of the phosphatidylinositol‐3‐kinase (PI3K) pathway is one of the most frequently
observed molecular alterations in many human malignancies, including head and neck …

Human papillomavirus (HPV)-induced cancers will remain a significant clinical challenge for
decades. Thus, the development of novel treatment strategies is urgently required, which …

Abstract The PI3K/AKT/mTOR signaling pathway has emerged as one of the most frequently
deregulated in head and neck squamous cell carcinomas (HNSCC). Numerous alterations …