Covalent entrapment of drug molecules within core-crosslinked polymeric micelles (CCPM)
represents an attractive approach to improve their therapeutic index. As an alternative to the …

Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

In clinical studies, drugs with hydrophobic characteristic usually reflect low bioavailability,
poor drug absorption, and inability to achieve the therapeutic concentration in blood. The …

Polymeric micelle (PM) is one of the most promising drug delivery systems for therapeutic
agents with poor solubility. Yet the in vivo fate of PM remains unclear due to the limitations in …

Micellization is the process of formation of micelles using different polymers mainly pluronic
(F127, F123, etc.). Polymers are used to formulate polymeric micelles that provide physical …

In the last decade, nanomedicine has arisen as an emergent area of medicine, which
studies nanometric systems, namely polymeric micelles (PMs), that increase the solubility …

Polymeric micelles (PM) are extensively used to improve the delivery of hydrophobic drugs.
Many different PM have been designed and evaluated over the years, and some of them …

This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

Block copolymer micelles are among the most extensively studied drug delivery systems
over the past three decades. They have been shown to enhance the aqueous solubility …

Micelles are self‐assembled nanoscaled aggregates from amphiphilic unimers and can be
used to encapsulate hydrophobic drugs. However, the dynamic exchanging of unimers …