Obesity and type 2 diabetes are causally related, yet there is considerable heterogeneity in
the consequences of both conditions and the mechanisms of action are poorly defined. Here …

In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …

Until recently, progress in identification of the genetic variants influencing predisposition to
common forms of diabetes and obesity has been slow, a sharp contrast to the large number …

Type 2 diabetes mellitus (T2D) and obesity already represent 2 of the most prominent risk
factors for cardiovascular disease, and are destined to increase in importance given the …

Common human diseases result from the interplay of many genes and environmental
factors. Therefore, a more integrative biology approach is needed to unravel the complexity …

Abstract Purpose of Review Our review provides a brief summary of the most recent
advances towards the identification of the genetic basis of specific aspects of obesity and the …

The increasing burden of obesity worldwide and its effect on cardiovascular disease (CVD)
risk is an opportunity for evaluation of preventive approaches. Both obesity and CVD have a …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta …

Abstract Type 2 diabetes (T2D) and obesity represent major challenges for global public
health. They are at the forefront of international efforts to identify the genetic variation …

The epidemic of obesity-associated diabetes is a major crisis in modern societies, in which
food is plentiful and exercise is optional. The biological basis of this problem has been …