Abstract The transcription factor Mohawk (Mkx) is expressed in developing tendons and is
an important regulator of tenogenic differentiation. However, the exact roles of Mkx in …

Cell-based or pharmacological approaches for promoting tendon repair are currently not
available because the molecular mechanisms of tendon development and healing are not …

Mohawk homeobox (MKX) has been demonstrated as a tendon/ligament specific
transcription factor. The aim of this study was to investigate the role of MKX in …

Meniscus tears are common knee injuries and a major osteoarthritis (OA) risk factor.
Knowledge gaps that limit the development of therapies for meniscus injury and …

After tendon injuries, biomechanical properties of the injured tendon are not fully recovered
in most cases. Modulation of signaling pathways, which are involved in tendon development …

Heterotopic ossification is the abnormal formation of mineralized bone in skin, muscle,
tendon, or other soft tissues. Tendon ossification often occurs from acute tendon injury or …

Mechanoforces experienced by an organ are translated into biological information for
cellular sensing and response. In mammals, the tendon connective tissue experiences and …

Tendons that connect muscles to bone are often the targets of sports injuries. The currently
unsatisfactory state of tendon repair is largely attributable to the limited understanding of …

The Mohawk homeobox (Mkx) gene encodes a new atypical homeodomain-containing
protein with transcriptional repressor activity. Mkx mRNA exhibited dynamic expression …

Both extrinsic and intrinsic tissues contribute to tendon repair, but the origin and molecular
functions of extrinsic tissues in tendon repair are not fully understood. Here we show that …