Photobiomodulation therapy moderates cancer cachexia-associated muscle wasting through activating PI3K/AKT/FoxO3a pathway

Y Li, Y Chen, Y Liao, T Huang, Q Tang, C He, L Xu… - Apoptosis, 2024 - Springer
Cancer cachexia-associated muscle wasting as a multifactorial wasting syndrome, is an
important factor affecting the long-term survival rate of tumor patients. Photobiomodulation …

Baoyuan Jiedu decoction alleviates cancer-induced myotube atrophy by regulating mitochondrial dynamics through p38 MAPK/PGC-1α signaling pathway

D Wang, W Chen, Q Bi, X Zong, J Ruan, X Yin… - Frontiers in …, 2020 - frontiersin.org
Cancer cachexia is a multifactorial syndrome characterized by continuous body wasting and
loss of skeletal muscle. Impaired mitochondria function is closely associated with muscle …

Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia

R Sartori, A Hagg, S Zampieri, A Armani… - Science translational …, 2021 - science.org
Most patients with advanced solid cancers exhibit features of cachexia, a debilitating
syndrome characterized by progressive loss of skeletal muscle mass and strength. Because …

Autophagy exacerbates muscle wasting in cancer cachexia and impairs mitochondrial function

F Penna, R Ballarò, P Martinez-Cristobal, D Sala… - Journal of molecular …, 2019 - Elsevier
Cancer cachexia is a multifactorial syndrome characterized by anorexia, weight loss and
muscle wasting that impairs patients' quality of life and survival. Aim of this work was to …

[HTML][HTML] Mitochondrial dysfunction in cancer cachexia: impact on muscle health and regeneration

M Beltrà, F Pin, R Ballarò, P Costelli, F Penna - Cells, 2021 - mdpi.com
Cancer cachexia is a frequently neglected debilitating syndrome that, beyond representing a
primary cause of death and cancer therapy failure, negatively impacts on patients' quality of …

Baoyuan Jiedu decoction alleviating cancer cachexia–Induced muscle atrophy by regulating muscle mitochondrial function in Apc Min/+ mice

B Zhang, Q Bi, S Huang, S Lv, X Zong… - Frontiers in …, 2022 - frontiersin.org
Cancer cachexia is a complex syndrome that leads to an ongoing loss of skeletal muscle
mass in many malignant tumors. Our previous studies have evaluated the effectiveness of …

Preventive effects of low‐intensity exercise on cancer cachexia–induced muscle atrophy

M Tanaka, K Sugimoto, T Fujimoto, K Xie… - The FASEB …, 2019 - Wiley Online Library
We hypothesized that low‐intensity endurance exercise might be more effective in
preventing cancer cachexia–induced muscle atrophy through both an increase in protein …

Exosomal plasminogen activator inhibitor-1 induces ionizing radiation-adaptive glioblastoma cachexia

E Shin, H Kang, H Lee, S Lee, J Jeon, K Seong… - Cells, 2022 - mdpi.com
Cancer cachexia is a muscle-wasting syndrome that leads to a severely compromised
quality of life and increased mortality. A strong association between cachexia and poor …

Cancer cachexia causes skeletal muscle damage via transient receptor potential vanilloid 2‐independent mechanisms, unlike muscular dystrophy

Y Iwata, N Suzuki, H Ohtake… - Journal of cachexia …, 2016 - Wiley Online Library
Background Muscle wasting during cancer cachexia contributes to patient morbidity.
Cachexia‐induced muscle damage may be understood by comparing its symptoms with …

Inhibition of activin-like kinase 4/5 attenuates cancer cachexia associated muscle wasting

S Levolger, EAC Wiemer, JLA van Vugt, SA Huisman… - Scientific reports, 2019 - nature.com
Cancer mediated activation of the ActRIIB-ALK4/5 heterodimer by myostatin is strongly
associated with muscle wasting. We investigated in vitro and in vivo the efficacy of ALK4/5 …