Pharmacotherapy options and drug development in managing periprosthetic joint infections in the elderly

A Macias-Valcayo, BG Pfang, A Auñón… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Prosthetic joint infections are an increasingly important problem among
patients undergoing arthroplasty procedures, and are associated with significant morbidity …

[HTML][HTML] Antibiotic therapy for prosthetic joint infections: an overview

B Le Vavasseur, V Zeller - Antibiotics, 2022 - mdpi.com
Prosthetic joint infection (PJI) is a severe complication after arthroplasty. Its management
combines surgical intervention, whose type depends on the clinical situation, and prolonged …

Curative treatment of prosthetic joint infection in patients younger than 80 vs. 80 or older

C Jamakorzyan, V Meyssonnier, Y Kerroumi, B Villain… - Joint Bone Spine, 2019 - Elsevier
Objective Prosthetic joint infection (PJI) is a serious complication of joint replacement
surgery. The major pharmacological and surgical treatments required by PJI increase the …

Drug treatments for prosthetic joint infections in the era of multidrug resistance

C Perez-Jorge, E Gomez-Barrena… - Expert Opinion on …, 2016 - Taylor & Francis
Introduction: Despite many advances, the management of prosthetic joint infection is still a
complex issue. Moreover, in recent years the problem of antimicrobial resistance has …

[HTML][HTML] Prosthetic joint infections in the elderly

G De Angelis, NT Mutters, L Minkley, F Holderried… - Infection, 2015 - Springer
Introduction Recent age-projection showed that the number of elderly is expected to rise
significantly over the next decades worldwide. Accordingly, the prevalence of chronic and …

Prosthetic joint infectionsin the elderly

N Rao, GL Soxman - Operative Techniques in Orthopaedics, 2002 - Elsevier
Total joint arthroplasty is among the most remarkable advances in orthopaedic surgery for
the elderly, enabling themto regain physical function and be free of pain. Although …

Systematic Review on the Current Situation and Development of Local Antimicrobial Agents in Revision Arthroplasty for Periprosthetic Joint Infection (PJI)

MA Jama, L Cao, Y Li, B Ji - Journal of Health and Medical …, 2024 - papers.ssrn.com
Total joint arthroplasty is a common surgery to treat degenerative joint disease, and it
significantly improves the lives of people suffering from conditions such as osteoarthritis …

Prolonged suppressive antibiotic therapy for prosthetic joint infection in the elderly: a national multicentre cohort study

V Prendki, T Ferry, P Sergent, E Oziol… - European Journal of …, 2017 - Springer
During prosthetic joint infection (PJI), optimal surgical management with exchange of the
device is sometimes impossible, especially in the elderly population. Thus, prolonged …

[HTML][HTML] Early-Outcome Differences between Acute and Chronic Periprosthetic Joint Infections—A Retrospective Single-Center Study

Y Youssef, E Roschke, N Dietze, AJ Dahse… - Antibiotics, 2024 - mdpi.com
Periprosthetic joint infections (PJI) are serious complications after arthroplasty, associated
with high morbidity, mortality, and complex treatment processes. The outcomes of different …

Prosthetic joint infections: single versus combination therapy

JR Samuel, FK Gould - Journal of antimicrobial chemotherapy, 2010 - academic.oup.com
Prosthetic joint replacement is increasingly used to alleviate pain and increase mobility.
Bone and joint infections remain a therapeutic dilemma for healthcare providers in all fields …