[HTML][HTML] Lessons learned from GWAS of asthma
Asthma is a common complex disease of the airways. Genome-wide association studies
(GWASs) of asthma have identified many risk alleles and loci that have been replicated in …
(GWASs) of asthma have identified many risk alleles and loci that have been replicated in …
Asthma genetics in the post-GWAS era
C Ober - Annals of the American Thoracic Society, 2016 - atsjournals.org
Genome-wide association studies (GWAS) of asthma have yielded exciting results and
identified novel risk alleles and loci. But, like other common complex diseases, asthma …
identified novel risk alleles and loci. But, like other common complex diseases, asthma …
Genome-wide association studies in asthma: what they really told us about pathogenesis
The next wave of asthma genetic studies will use full-genome sequencing and overcome
most GWAS-associated problems. It will be the last step of a century-long search for asthma …
most GWAS-associated problems. It will be the last step of a century-long search for asthma …
[HTML][HTML] The genetics of asthma and allergic disorders
ME March, PMA Sleiman… - Discovery …, 2011 - discoverymedicine.com
Asthma and allergic diseases are complex conditions caused by a combination of genetic
and environmental factors. More than 100 genes have been associated with asthma and …
and environmental factors. More than 100 genes have been associated with asthma and …
Decoding the genetic and epigenetic basis of asthma
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions
X Li, TD Howard, SL Zheng, T Haselkorn… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Asthma is a heterogeneous disease that is caused by the interaction of
genetic susceptibility with environmental influences. Genome-wide association studies …
genetic susceptibility with environmental influences. Genome-wide association studies …
[HTML][HTML] Advances in asthma and allergic disease genetics: Is bigger always better?
N Schoettler, E Rodríguez, S Weidinger… - Journal of Allergy and …, 2019 - Elsevier
This review focuses on genome-wide association studies (GWASs) of asthma and allergic
diseases published between January 1, 2018, and June 30, 2019. During this time period …
diseases published between January 1, 2018, and June 30, 2019. During this time period …
Genome‐wide association studies for discovery of genes involved in asthma
L Akhabir, AJ Sandford - Respirology, 2011 - Wiley Online Library
Asthma is the result of a complex interaction between environmental factors and genetic
variants that confer susceptibility. Studies of the genetics of asthma have previously been …
variants that confer susceptibility. Studies of the genetics of asthma have previously been …
Lessons from ten years of genome‐wide association studies of asthma
CT Vicente, JA Revez… - Clinical & translational …, 2017 - Wiley Online Library
Twenty‐five genome‐wide association studies (GWAS) of asthma were published between
2007 and 2016, the largest with a sample size of 157242 individuals. Across these studies …
2007 and 2016, the largest with a sample size of 157242 individuals. Across these studies …
[HTML][HTML] Genomic predictors of asthma phenotypes and treatment response
N Hernandez-Pacheco, M Pino-Yanes… - Frontiers in …, 2019 - frontiersin.org
Asthma is a complex respiratory disease considered as the most common chronic condition
in children. A large genetic contribution to asthma susceptibility is predicted by the clustering …
in children. A large genetic contribution to asthma susceptibility is predicted by the clustering …