Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours

J Garg, K Pathania, SP Sah, SV Pawar - Future Journal of Pharmaceutical …, 2022 - Springer
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …

Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases

C Tapeinos, M Battaglini, G Ciofani - Journal of Controlled Release, 2017 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) comprise a
category of versatile drug delivery systems that have been used in the biomedical field for> …

Advances in brain drug targeting and delivery: limitations and challenges of solid lipid nanoparticles

M Patel, EB Souto, KK Singh - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: With the advancement in the field of medical colloids and interfacial sciences,
the life expectancy has been greatly improved. In addition, changes in the human lifestyle …

Nanostructured lipid carriers (NLC) system: A novel drug targeting carrier

VR Salvi, P Pawar - Journal of Drug Delivery Science and Technology, 2019 - Elsevier
Lipid nanocarriers are developed as an alternative to polymeric nanoparticles, liposomes
and emulsions. Further, Nanostructured Lipid Nanocarriers are the second generation lipid …

[HTML][HTML] Surface-modified lipid nanocarriers for crossing the blood-brain barrier (BBB): A current overview of active targeting in brain diseases

MI Teixeira, CM Lopes, MH Amaral, PC Costa - Colloids and Surfaces B …, 2023 - Elsevier
The blood-brain barrier (BBB) restricts the access of therapeutic agents to the brain,
complicating the treatment of neurological diseases, such as Alzheimer's disease (AD) …

Solid lipid-based nanocarriers as efficient targeted drug and gene delivery systems

JEN Dolatabadi, Y Omidi - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
Most of the active pharmaceutical ingredients are often prone to display low bioavailability,
biological degradation and inadvertent intrinsic side effects. To circumvent such obstacles …

Lipid nanostructures for targeting brain cancer

H Nsairat, D Khater, F Odeh, F Al-Adaileh, S Al-Taher… - Heliyon, 2021 - cell.com
Advancements in both material science and bionanotechnology are transforming the health
care sector. To this end, nanoparticles are increasingly used to improve diagnosis …

Solid lipid nanoparticles (SLNs): an advanced drug delivery system targeting brain through BBB

MK Satapathy, TL Yen, JS Jan, RD Tang, JY Wang… - Pharmaceutics, 2021 - mdpi.com
The blood–brain barrier (BBB) plays a vital role in the protection and maintenance of
homeostasis in the brain. In this way, it is an interesting target as an interface for various …

Recent progress of drug nanoformulations targeting to brain

AR Khan, X Yang, M Fu, G Zhai - Journal of Controlled Release, 2018 - Elsevier
Most of the potential therapeutic agents capable to modulate the pathophysiology or treat
the neurological disorders and brain tumors are useless in the current modern and …