Neuroinflammatory mediators play a crucial role in the pathophysiology of brain ischemia,
exerting either deleterious effects on the progression of tissue damage or beneficial roles …

Abnormal expression of matrix metalloproteinases (MMPs) has been implicated in the
pathophysiology of neuroinflammatory processes that accompany most central nervous …

Stroke is the second leading cause of death worldwide and has two major subtypes:
ischemic stroke and hemorrhagic stroke. Neuroinflammation is a pathological hallmark of …

Post-ischemic inflammation is important in ischemic stroke pathology. However, details of
the inflammation process, its resolution after stroke and its effect on pathology and neural …

Ischemic stroke is a leading cause of death and disability in developed countries. Yet, in
spite of substantial research and development efforts, no specific therapy for stroke is …

Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

Contrary to previous dogmas, it is now well established that brain cells can produce
cytokines and chemokines, and can express adhesion molecules that enable an in situ …

We review the molecular and biochemical events that occur within the brain during cerebral
ischemia, based on recent investigations of focal cerebral ischemia models. Occlusion of the …

Numerous studies have indicated that inflammation plays a key role in ischaemic brain
injury. Brain ischaemia–reperfusion‐induced inflammatory responses include increased …