Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy

F Galli, JV Aguilera, B Palermo, SN Markovic… - Journal of experimental …, 2020 - Springer
Tumor-infiltrating immune cells play a key role against cancer. However, malignant cells are
able to evade the immune response and establish a very complex balance in which different …

Immune landscape in tumor microenvironment: Implications for biomarker development and immunotherapy

K Pérez-Romero, RM Rodríguez, A Amedei… - International journal of …, 2020 - mdpi.com
Integration of the tumor microenvironment as a fundamental part of the tumorigenic process
has undoubtedly revolutionized our understanding of cancer biology. Increasing evidence …

Behavior of immune players in the tumor microenvironment

MJ Pittet - Current opinion in oncology, 2009 - journals.lww.com
Behavior of immune players in the tumor microenvironment : Current Opinion in Oncology
Behavior of immune players in the tumor microenvironment : Current Opinion in Oncology Log …

[HTML][HTML] High-dimensional immune-profiling in cancer: implications for immunotherapy

S Chuah, V Chew - Journal for immunotherapy of cancer, 2020 - ncbi.nlm.nih.gov
Immunotherapy is a rapidly growing field for cancer treatment. In contrast to conventional
cancer therapies, immunotherapeutic strategies focus on reactivating the immune system to …

Advancements in cancer immunotherapies

R Roy, SK Singh, S Misra - Vaccines, 2022 - mdpi.com
Recent work has suggested involvement of the immune system in biological therapies
specifically targeting tumor microenvironment. Substantial advancement in the treatment of …

Immune microenvironment in tumor progression: characteristics and challenges for therapy

V Chew, HC Toh, JP Abastado - Journal of oncology, 2012 - Wiley Online Library
The tumor microenvironment plays a critical role in cancer development, progression, and
control. The molecular and cellular nature of the tumor immune microenvironment influences …

Heterogeneity of the tumor immune microenvironment and its clinical relevance

Q Jia, A Wang, Y Yuan, B Zhu, H Long - Experimental hematology & …, 2022 - Springer
During the course of tumorigenesis and subsequent metastasis, malignant cells gradually
diversify and become more heterogeneous. Consequently, the tumor mass might be …

Emerging and evolving concepts in cancer immunotherapy imaging

L Dercle, S Sun, RD Seban, A Mekki, R Sun, L Tselikas… - Radiology, 2023 - pubs.rsna.org
Criteria based on measurements of lesion diameter at CT have guided treatment with
historical therapies due to the strong association between tumor size and survival. Clinical …

Immune cells within the tumor microenvironment: Biological functions and roles in cancer immunotherapy

X Lei, Y Lei, JK Li, WX Du, RG Li, J Yang, J Li, F Li… - Cancer letters, 2020 - Elsevier
The immune cells within the tumor microenvironment (TME) play important roles in
tumorigenesis. It has been known that these tumor associated immune cells may possess …

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

Y Zhang, Z Zhang - Cellular & molecular immunology, 2020 - nature.com
Immunotherapy has revolutionized cancer treatment and rejuvenated the field of tumor
immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and …