Background: Amyotrophic lateral sclerosis (ALS) is an incurable disease. There are vigorous
attempts to develop treatments to reduce the effects of this disease, and among these …

Objective: To analyze the safety and clinical effect of stem cell therapy in ALS. Methods: In
phase I of the trial, ALS subjects have been intrathecally transplanted with autologous bone …

Stem cell-based treatments have emerged as potentially effective approaches to delay the
progression of amyotrophic lateral sclerosis (ALS). This study was designed as a single …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a heterogeneous
course that ultimately leads to death. Currently, there is no cure, and new treatments that can …

Introduction: No cure has been found for Amy-otrophic Lateral Sclerosis (ALS) despite
several studies using drugs or related compounds. Background: Cellular, molecular and pre …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the
degeneration of both upper and lower motor neurons. Patients show both motor and extra …

Bone marrow mesenchymal stromal cells (MSCs) can modify disease progression in
amyotrophic lateral sclerosis (ALS) model. However, there are currently no accurate …

Background aims Thanks to their immunomodulatory, tissue-protective and regenerative
properties, mesenchymal stromal cells (MSCs) are a promising approach for amyotrophic …

Amyotrophic Lateral Sclerosis (ALS) is a devastating incurable disease. Stem-cell-based
therapies represent a new possible strategy for ALS clinical research. The objectives of this …

Transplantation of several types of stem cells (SC) for the treatment of amyotrophic lateral
sclerosis (ALS) has been evaluated in numerous Phase I/II clinical trials with inconclusive …