Metformin: a review of its potential indications

YW Wang, SJ He, X Feng, J Cheng… - Drug design …, 2017 - Taylor & Francis
Metformin is the most commonly prescribed drug for type 2 diabetes mellitus. In recent years,
in addition to glucose lowering, several studies have presented evidence suggesting some …

Metformin revisited: re‐evaluation of its properties and role in the pharmacopoeia of modern antidiabetic agents

MO Goodarzi, M Bryer‐Ash - Diabetes, Obesity and …, 2005 - Wiley Online Library
Background: The usefulness of metformin as an oral antidiabetic agent is widely accepted.
However, several other classes of oral antidiabetic agents have been recently introduced …

The current and potential therapeutic use of metformin—the good old drug

J Drzewoski, M Hanefeld - Pharmaceuticals, 2021 - mdpi.com
Metformin, one of the oldest oral antidiabetic agents and still recommended by almost all
current guidelines as the first-line treatment for type 2 diabetes mellitus (T2DM), has become …

[HTML][HTML] Metformin: current knowledge

H Nasri, M Rafieian-Kopaei - … of research in medical sciences: the …, 2014 - ncbi.nlm.nih.gov
Diabetes mellitus is a group of metabolic disorders in which the blood glucose is higher than
normal levels, due to insufficiency of insulin release or improper response of cells to insulin …

[HTML][HTML] Metformin and its clinical use: new insights for an old drug in clinical practice

AFG Cicero, E Tartagni, S Ertek - Archives of medical science: AMS, 2012 - ncbi.nlm.nih.gov
Metformin is generally recommended as first-line treatment in type 2 diabetes, especially in
overweight patients, but in recent years new indications for its use have emerged. Metformin …

Metformin: the hidden chronicles of a magic drug

K Mahmood, M Naeem, NA Rahimnajjad - European journal of internal …, 2013 - Elsevier
Metformin, a biguanide is well known treatment for type 2 diabetes mellitus that has diverse
mechanism of actions. Various studies have elucidated the role of this drug in different …

[HTML][HTML] Metformin and its benefits for various diseases

Z Lv, Y Guo - Frontiers in endocrinology, 2020 - frontiersin.org
Metformin is a widely used biguanide drug due to its safety and low cost. It has been used
for over 60 years to treat type 2 diabetes at the early stages because of its outstanding ability …

Metformin in therapeutic applications in human diseases: Its mechanism of action and clinical study

Y Du, YJ Zhu, YX Zhou, J Ding, JY Liu - Molecular Biomedicine, 2022 - Springer
Metformin, a biguanide drug, is the most commonly used first-line medication for type 2
diabetes mellites due to its outstanding glucose-lowering ability. After oral administration of …

Metformin: new understandings, new uses

RS Hundal, SE Inzucchi - Drugs, 2003 - Springer
Metformin, a biguanide, has been available in the US for the treatment of type 2 diabetes
mellitus for nearly 8 years. Over this period of time, it has become the most widely prescribed …

Metformin: a review of its metabolic effects

K Cusi, RA DeFronzo - Diabetes Reviews, 1998 - scholars.uthscsa.edu
Metformin is a biguanide that has been used worldwide for the treatment of type 2 diabetes
for the past 4 decades. It improves glycemic control by enhancing insulin sensitivity in liver …