Parallel signal processing among mammalian MAPKs

E Cano, LC Mahadevan - Trends in biochemical sciences, 1995 - cell.com
The intracellular signalling field is dominated by the mitogen-activated protein kinase
(MAPK) cascade and its control, which involves the small GTPase Ras and sequential …

The MAP kinase signaling cascades: a system of hundreds of components regulates a diverse array of physiological functions

Y Keshet, R Seger - MAP Kinase Signaling Protocols: Second Edition, 2010 - Springer
Sequential activation of kinases within the mitogen-activated protein (MAP) kinase (MAPK)
cascades is a common, and evolutionary-conserved mechanism of signal transduction. Four …

Counting on mitogen-activated protein kinases—ERKs 3, 4, 5, 6, 7 and 8

MA Bogoyevitch, NW Court - Cellular signalling, 2004 - Elsevier
Signal transduction pathways in eukaryotic cells integrate diverse extracellular signals, and
regulate complex biological responses such as growth, differentiation and death. One group …

Role of MAPKs in development and differentiation: lessons from knockout mice

M Aouadi, B Binetruy, L Caron, Y Le Marchand-Brustel… - Biochimie, 2006 - Elsevier
The ERK, p38MAPK, JNK mitogen-activated protein kinases (MAPKs) are intracellular
signaling pathways that play a pivotal role in many essential cellular processes such as …

[HTML][HTML] Sounding the alarm: protein kinase cascades activated by stress and inflammation

JM Kyriakis, J Avruch - Journal of Biological Chemistry, 1996 - ASBMB
Eukaryotic cells respond to extracellular stimuli by recruiting signal transduction pathways,
many of which employ protein Ser/Thr kinases of the ERK1 family. The ubiquity of ERKs and …

[PDF][PDF] Distantly related cousins of MAP kinase: biochemical properties and possible physiological functions

Y Miyata, E Nishida - Biochemical and biophysical research …, 1999 - academia.edu
MAP kinases have been established to be key regulators of cellular signal transduction
systems and are conserved from baker's yeast to human beings. Until now, three major …

New insights into the control of MAP kinase pathways

J English, G Pearson, J Wilsbacher, J Swantek… - Experimental cell …, 1999 - Elsevier
Mitogen-activated protein (MAP) kinases, found in all eukaryotes, are common participants
in signal transduction pathways from the membrane to the nucleus [1–3]. They signal in a …

Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members

JA Frost, S Xu, MR Hutchison, S Marcus… - Molecular and cellular …, 1996 - Taylor & Francis
The mitogen-activated protein (MAP) kinases are a family of serine/threonine kinases that
are regulated by distinct extracellular stimuli. The currently known members include …

Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5

P Déléris, J Rousseau, P Coulombe… - Journal of cellular …, 2008 - Wiley Online Library
Mitogen‐activated protein (MAP) kinases are typical examples of protein kinases whose
enzymatic activity is mainly controlled by activation loop phosphorylation. The classical MAP …

[HTML][HTML] MAP kinase pathways

DK Morrison - Cold Spring Harbor perspectives in …, 2012 - cshperspectives.cshlp.org
MAP Kinase Pathways Cold Spring Harbor Perspectives in Biology Skip to main page content
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