Inducing a long-lasting as well as broad and potent immune response by generating broadly
neutralizing antibodies is a major goal and at the same time the main challenge of …

Nanoparticulate vaccines can potentiate immune responses by site-specific drainage to
lymph nodes (LNs). This approach may benefit from a nanoparticle engineering method with …

Polymeric nanoparticulate carriers play an important role and holding a significant potential
for the development of novel immunomodulatory agents as easily they are taken up by …

Vaccination has a great impact on the prevention and control of infectious diseases.
However, there are still many infectious diseases for which an effective vaccine is missing …

Nanoparticulate carriers are particularly promising and versatile in stimulating immune
response. Indeed, nanotechnology allows the creation of structures that exploit the inherent …

Inducing immune responses protecting from HIV infection or at least controlling replication
poses a huge challenge to modern vaccinology. An increasingly discussed strategy to elicit …

Vaccination plays a crucial role in the control of infectious diseases, but often fails to
eradicate certain refractory infections for which the development of an effective vaccine is …

Providing the optimum treatment of AIDS is a major challenge in the 21st Century. HIV is
localised and harboured in certain inaccessible compartments of the body, such as the CNS …

It is becoming increasingly clear that HIV-1 vaccine research might benefit greatly from using
nanoparticles presenting Env trimers, particularly during the priming stage of immunization …

Vaccines remain the most effective way to protect populations against deathly infectious
diseases. Several disadvantages associated with the traditional vaccines that use whole …