Increased susceptibility against Cryptococcus neoformans of lupus mouse models (pristane-induction and FcGRIIb deficiency) is associated with activated …

S Surawut, J Makjaroen, A Thim-Uam… - Journal of …, 2019 - Springer
The severity of cryptococcosis in lupus from varying genetic-backgrounds might be different
due to the heterogeneity of lupus-pathogenesis. This study explored cryptococcosis in lupus …

The role of macrophages in the susceptibility of Fc gamma receptor IIb deficient mice to Cryptococcus neoformans

S Surawut, T Ondee, S Taratummarat, T Palaga… - Scientific reports, 2017 - nature.com
Dysfunctional polymorphisms of FcγRIIb, an inhibitory receptor, are associated with
Systemic Lupus Erythaematosus (SLE). Cryptococcosis is an invasive fungal infection in …

Altered immune response differentially enhances susceptibility to Cryptococcus neoformans and Cryptococcus gattii infection in mice expressing the HIV-1 transgene

K Leongson, V Cousineau-Côté, M Goupil… - Infection and …, 2013 - Am Soc Microbiol
Cryptococcus neoformans var. grubii is the most frequent cause of AIDS-associated
cryptococcosis worldwide, while Cryptococcus gattii usually infects immunocompetent …

Inbred SJL mice recapitulate human resistance to Cryptococcus infection due to differential immune activation

MJ Davis, RE Martin, GM Pinheiro, ES Hoke, S Moyer… - Mbio, 2023 - Am Soc Microbiol
Cryptococcosis remains a significant threat to human health. While the popular C57BL/6J
mouse model of cryptococcosis has some advantages, there are some serious shortcomings …

Improved Survival of Mice Deficient in Secretory Immunoglobulin M following Systemic Infection with Cryptococcus neoformans

KS Subramaniam, K Datta, MS Marks… - Infection and …, 2010 - Am Soc Microbiol
Cryptococcus neoformans causes severe, and often fatal, disease (cryptococcosis) in
immunocompromised patients, particularly in those with HIV/AIDS. Although resistance to …

[HTML][HTML] Protective immunity against pulmonary cryptococcosis is associated with STAT1-mediated classical macrophage activation

SE Hardison, G Herrera, ML Young… - The Journal of …, 2012 - journals.aai.org
Experimental pulmonary Cryptococcus neoformans infection in BALB/c mice is associated
with polarized Th2-type cytokine production, alternative macrophage activation, and severe …

Fluconazole Alters the Polysaccharide Capsule of Cryptococcus gattii and Leads to Distinct Behaviors in Murine Cryptococcosis

JRA Santos, RA Holanda, S Frases, M Bravim… - PLoS …, 2014 - journals.plos.org
Cryptococcus gattii is an emergent human pathogen. Fluconazole is commonly used for
treatment of cryptococcosis, but the emergence of less susceptible strains to this azole is a …

Immunosuppression in experimental cryptococcosis: variation of splenic and thymic populations and expression of class II major histocompatibility complex gene …

CE Sotomayor, HR Rubinstein, CM Riera… - Clinical immunology and …, 1995 - Elsevier
Previous studies from our laboratory have shown that infection with Cryptococcus
neoformans can trigger the production of a series of suppressor cells that specifically inhibit …

Cooperative Role of Macrophages and Neutrophils in Host Antiprotozoan Resistance in Mice Acutely Infected with Cryptosporidium parvum

D Takeuchi, VC Jones, M Kobayashi… - Infection and …, 2008 - Am Soc Microbiol
Severe experimental infections with Cryptosporidium parvum have been reported in
immunocompromised animals such as SCID mice (mice without functional T cells and B …

The Relative Susceptibility of Mouse Strains to Pulmonary Cryptococcus neoformans Infection Is Associated with Pleiotropic Differences in the Immune Response

O Zaragoza, M Alvarez, A Telzak, J Rivera… - Infection and …, 2007 - Am Soc Microbiol
ABSTRACT CBA/J mice were highly susceptible to intratracheal (it) Cryptococcus
neoformans infection relative to BALB/c mice, while both strains were equally susceptible to …