Tetraspanin CD151 promotes initial events in human cytomegalovirus infection

D Hochdorfer, L Florin, C Sinzger, D Lieber - Journal of Virology, 2016 - Am Soc Microbiol
Human cytomegalovirus (HCMV), a betaherpesvirus, can cause life-threatening disease in
immunocompromised individuals. Viral envelope glycoproteins that mediate binding to and …

CD147 promotes entry of pentamer-expressing human cytomegalovirus into epithelial and endothelial cells

AL Vanarsdall, SR Pritchard, TW Wisner, J Liu… - MBio, 2018 - Am Soc Microbiol
Human cytomegalovirus (HCMV) replicates in many diverse cell types in vivo, and entry into
different cells involves distinct entry mechanisms and different envelope glycoproteins …

The human cytomegalovirus trimer and pentamer promote sequential steps in entry into epithelial and endothelial cells at cell surfaces and endosomes

J Liu, TS Jardetzky, AL Chin, DC Johnson… - Journal of …, 2018 - Am Soc Microbiol
Human cytomegalovirus (HCMV) infects a wide variety of human cell types by different entry
pathways that involve distinct envelope glycoprotein complexes that include gH/gL, a trimer …

Cellular integrins function as entry receptors for human cytomegalovirus via a highly conserved disintegrin-like domain

AL Feire, H Koss, T Compton - Proceedings of the National …, 2004 - National Acad Sciences
Human cytomegalovirus (HCMV) is capable of manifesting disease in nearly every organ
system in immunocompromised patients. This broad pathogenic tropism correlates with the …

[HTML][HTML] Pathogen at the gates: human cytomegalovirus entry and cell tropism

CC Nguyen, JP Kamil - Viruses, 2018 - mdpi.com
The past few years have brought substantial progress toward understanding how human
cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that …

Initiation of human cytomegalovirus infection requires initial interaction with cell surface heparan sulfate

T Compton, DM Nowlin, NR Cooper - Virology, 1993 - Elsevier
In this report, we demonstrate that the initial event in human cytomegalovirus (HCMV)
infection is attachment to extracellular heparan sulfate. Further, this interaction is important …

The CD46 ectodomain participates in human cytomegalovirus infection of epithelial cells

AJ Parsons, KR Stein, KE Atanasoff… - Journal of General …, 2023 - microbiologyresearch.org
Human cytomegalovirus (HCMV) primary infections are typically asymptomatic in healthy
individuals yet can cause increased morbidity and mortality in organ transplant recipients …

Identification of binary interactions between human cytomegalovirus virion proteins

SL Phillips, WA Bresnahan - Journal of virology, 2011 - Am Soc Microbiol
Human cytomegalovirus (HCMV) virions are composed of a DNA-containing nucleocapsid
surrounded by a tegument layer and host-derived lipid envelope studded with virally …

[HTML][HTML] Early events in human cytomegalovirus infection

T Compton, A Feire - 2011 - europepmc.org
All viruses must deliver their genomes to host cells to initiate infection. The plasma
membrane together with cell surface constituents serve as initial barriers to entry as well as …

[HTML][HTML] Human cytomegalovirus tegument proteins (pp65, pp71, pp150, pp28)

JP Tomtishen III - Virology journal, 2012 - Springer
Human cytomegalovirus (HCMV), a member of the Betaherpesvirinae sub-family of
Herpesviridae family, is a widespread pathogen that infects a majority of the world's …