Stable self-assembly of bovine α-lactalbumin exhibits target-specific antiproliferative activity in multiple cancer cells

S Mahanta, S Paul - ACS Applied Materials & Interfaces, 2015 - ACS Publications
Self-assembly of a protein is a natural phenomenon; however, the process can be
performed under a suitable condition in vitro. Since proteins are nontoxic, biodegradable …

Designing Multifunctional Biomaterials via Protein Self‐Assembly

A Solomonov, A Kozell… - Angewandte Chemie …, 2024 - Wiley Online Library
Protein self‐assembly is a fundamental biological process where proteins spontaneously
organize into complex and functional structures without external direction. This process is …

Protein self-assembly: technology and strategy

L Zhao, S Qiao, J Liu - Science China Chemistry, 2016 - Springer
Proteins, as the premier building blocks in nature, exhibit extraordinary ability in life activities
during which process proteins mostly self-assemble into large complexes to exert prominent …

Enzyme‐instructed self‐assembly (EISA) and hydrogelation of peptides

J Gao, J Zhan, Z Yang - Advanced Materials, 2020 - Wiley Online Library
Self‐assembly is a powerful tool for constructing supramolecular materials for many
applications, ranging from energy harvesting to biomedicine. Among the methods to prepare …

A facile approach for crosslinker free nano self assembly of protein for anti-tumor drug delivery: Factors' optimization, characterization and in vitro evaluation

S Asghar, JMM Salmani, W Hassan, Y Xie… - European Journal of …, 2014 - Elsevier
We report crosslinker free self assembly of bovine serum albumin (BSA) and a hydrophobic
payload paclitaxel (PTX), into nanoparticles by harnessing the temperature driven unfolding …

Supramolecular nanoassembly of lysozyme and α-lactalbumin (apo α-LA) exhibits selective cytotoxicity and enhanced bioavailability of curcumin to cancer cells

P Somu, S Paul - Colloids and Surfaces B: Biointerfaces, 2019 - Elsevier
Hybrid supramolecular spherical nanoassembly of hen egg white lysozyme and bovine apo
α lactalbumin (SN LYZ-BLA) was prepared with a mean size of˜ 55.2 nm using an optimized …

Emerging biological materials through molecular self-assembly

S Zhang - Biotechnology advances, 2002 - Elsevier
Understanding of new materials at the molecular level has become increasingly critical for a
new generation of nanomaterials for nanotechnology, namely, the design, synthesis and …

[HTML][HTML] Chemical reactions directed peptide self-assembly

DB Rasale, AK Das - International journal of molecular sciences, 2015 - mdpi.com
Fabrication of self-assembled nanostructures is one of the important aspects in nanoscience
and nanotechnology. The study of self-assembled soft materials remains an area of interest …

Preorganization increases the self-assembling ability and antitumor efficacy of peptide nanomedicine

C Liang, Z Wang, T Xu, Y Chen, D Zheng… - … applied materials & …, 2020 - ACS Publications
Inspired by the biological process of phosphorylation for which different sites of the same
protein may have different activities and functions, we utilized phosphatase-based enzyme …

Self-assembled serum albumin–poly (l-lactic acid) nanoparticles: a novel nanoparticle platform for drug delivery in cancer

L Dai, CX Li, KF Liu, HJ Su, BQ Chen, GF Zhang, J He… - RSC …, 2015 - pubs.rsc.org
We developed a new self-assembled bovine serum albumin–poly (L-lactic acid)
nanoparticle platform for anticancer drug delivery made from a bovine serum albumin–poly …