Anticholinergics: theoretical and clinical overview

PS Nishtala, MS Salahudeen… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Anticholinergics are a class of medicines that block the neurotransmitter,
acetylcholine, in the brain and peripheral tissues. Medicines with anticholinergic activity are …

Systematic review of anticholinergic risk scales in older adults

CE Durán, M Azermai, RH Vander Stichele - European journal of clinical …, 2013 - Springer
Background Anticholinergic drugs are often involved in explicit criteria for inappropriate
prescribing in older adults. Several scales were developed for screening of anticholinergic …

Anticholinergic burden: considerations for older adults

L Kouladjian O'Donnell, D Gnjidic… - Journal of Pharmacy …, 2017 - Wiley Online Library
Anticholinergic medications are frequently used in older adults to manage a wide range of
chronic diseases. Anticholinergic burden associated with the use of multiple medications …

Impact of anticholinergics on the aging brain: a review and practical application

M Boustani, N Campbell, S Munger, I Maidment… - Aging health, 2008 - Taylor & Francis
Objective: in an effort to enhance medication prescribing for older adults and reduce the
burden of cognitive impairment, this paper reviews the literature regarding the negative …

Drugs with anticholinergic properties: a current perspective on use and safety

P Gerretsen, BG Pollock - Expert opinion on drug safety, 2011 - Taylor & Francis
Introduction: Many commonly used drugs have primary or secondary anticholinergic effects
contributing to adverse outcomes ranging from mild-to-severe to potentially lethal …

Anticholinergic medication use and dementia: latest evidence and clinical implications

SL Gray, JT Hanlon - Therapeutic advances in drug safety, 2016 - journals.sagepub.com
Use of medications with anticholinergic activity is widespread in older adults. Several
studies have highlighted that anticholinergic use may be associated with an increased risk …

Anticholinergic drugs and negative outcomes in the older population: from biological plausibility to clinical evidence

A Collamati, AM Martone, A Poscia, V Brandi… - Aging clinical and …, 2016 - Springer
The use of medication with anticholinergic properties is widespread among older subjects.
Many drugs of common use such as antispasmodics, bronchodilators, antiarrhythmics …

Anticholinergic drug burden in older people's brain–how well is it measured?

H Kersten, TB Wyller - Basic & clinical pharmacology & …, 2014 - Wiley Online Library
Concurrent use of several drugs with potential anticholinergic properties is highly prevalent
in the elderly. Methods to determine the overall anticholinergic drug burden have been …

Association between anticholinergic drug burden and mortality in older people: a systematic review

S Ali, GM Peterson, LR Bereznicki… - European Journal of …, 2020 - Springer
Purpose The purpose of the study is to conduct a systematic review of studies examining the
association between anticholinergic burden and mortality in older individuals. Methods A …

[HTML][HTML] The anticholinergic burden: from research to practice

SN Hilmer, D Gnjidic - Australian Prescriber, 2022 - ncbi.nlm.nih.gov
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