Relationship of plasma biomarkers to digital cognitive tests in Alzheimer's disease
INTRODUCTION A major limitation in Alzheimer's disease (AD) research is the lack of the
ability to measure cognitive performance at scale—robustly, remotely, and frequently …
ability to measure cognitive performance at scale—robustly, remotely, and frequently …
Performance and validation of a digital memory test across the Alzheimer's Disease continuum
Digital cognitive testing using online platforms has emerged as a potentially transformative
tool in clinical neuroscience. In theory, it could provide a powerful means of screening for …
tool in clinical neuroscience. In theory, it could provide a powerful means of screening for …
Association of plasma biomarkers of Alzheimer's disease and related disorders with cognition and cognitive decline: The MYHAT population‐based study
Y Zhang, PCL Ferreira, E Jacobsen… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Plasma biomarkers of Alzheimer's disease and related dementias predict
global cognitive performance and decline over time; it remains unclear how they associate …
global cognitive performance and decline over time; it remains unclear how they associate …
Amyloid-β, tau, and cognition in cognitively normal older individuals: examining the necessity to adjust for biomarker status in normative data
We investigated whether amyloid-β (Aβ) and tau affected cognition in cognitively normal
(CN) individuals, and whether norms for neuropsychological tests based on biomarker …
(CN) individuals, and whether norms for neuropsychological tests based on biomarker …
Current advances in digital cognitive assessment for preclinical Alzheimer's disease
There is a pressing need to capture and track subtle cognitive change at the preclinical
stage of Alzheimer's disease (AD) rapidly, cost‐effectively, and with high sensitivity …
stage of Alzheimer's disease (AD) rapidly, cost‐effectively, and with high sensitivity …
Combining plasma phospho-tau and accessible measures to evaluate progression to Alzheimer's dementia in mild cognitive impairment patients
A Pichet Binette, S Palmqvist, D Bali, G Farrar… - Alzheimer's Research & …, 2022 - Springer
Background Up to now, there are no clinically available minimally invasive biomarkers to
accurately identify mild cognitive impairment (MCI) patients who are at greater risk to …
accurately identify mild cognitive impairment (MCI) patients who are at greater risk to …
Using a Digital Neuro Signature to measure longitudinal individual-level change in Alzheimer's disease: the Altoida large cohort study
Conventional neuropsychological assessments for Alzheimer's disease are burdensome
and inaccurate at detecting mild cognitive impairment and predicting Alzheimer's disease …
and inaccurate at detecting mild cognitive impairment and predicting Alzheimer's disease …
Plasma biomarker profiles and the correlation with cognitive function across the clinical spectrum of Alzheimer's disease
Z Xiao, X Wu, W Wu, J Yi, X Liang, S Ding… - Alzheimer's Research & …, 2021 - Springer
Background Plasma biomarkers showed a promising value in the disease diagnosis and
management of Alzheimer's disease (AD). However, profiles of the biomarkers and the …
management of Alzheimer's disease (AD). However, profiles of the biomarkers and the …
Digital cognitive assessments as low-burden markers for predicting future cognitive decline and tau accumulation across the Alzheimer's spectrum
CR Vanderlip, CEL Stark - bioRxiv, 2024 - biorxiv.org
Digital cognitive assessments, particularly those that can be done at home, present as low
burden biomarkers for participants and patients alike, but their effectiveness in diagnosis of …
burden biomarkers for participants and patients alike, but their effectiveness in diagnosis of …
Remote and unsupervised digital memory assessments can reliably detect cognitive impairment in Alzheimer's disease
INTRODUCTION Remote unsupervised cognitive assessments have the potential to
complement and facilitate cognitive assessment in clinical and research settings. METHODS …
complement and facilitate cognitive assessment in clinical and research settings. METHODS …