Optimisation de l'antibiothérapie chez le patient obèse en réanimation

M Hites, FS Taccone - Réanimation, 2015 - Springer
As the prevalence of obesity increases worldwide, clinicians will be more and more
frequently confronted with obese, critically ill patients. Optimal administration of antibiotics is …

Optimization of antibiotic therapy in the obese, critically ill patient

M Hites, FS Taccone - Médecine Intensive Réanimation, 2015 - revue-mir.srlf.org
Résumé Comme la prévalence de l'obésité augmente dans le monde, le clinicien sera de
plus en plus fréquemment confronté à des patients obèses en réanimation. Il est …

Dosing in obese critically ill patients

M Hites, FS Taccone - Antibiotic Pharmacokinetic/Pharmacodynamic …, 2018 - Springer
As the prevalence of obesity continues to rise significantly worldwide, an increasing number
of overweight patients are expected to present to hospital with various pathological …

Therapeutic Drug Monitoring of Antimicrobials in Critically Ill Obese Patients

J Gorham, FS Taccone, M Hites - Antibiotics, 2023 - mdpi.com
Obesity is a significant global public health concern that is associated with an elevated risk
of comorbidities as well as severe postoperative and nosocomial infections. The treatment of …

[PDF][PDF] Aktuální doporučení pro dávkování antibiotik u obézních pacientů

J Strojil - casopisvnitrnilekarstvi.cz
Obesity is a growing societal and population health problem the prevalence of which has
increased significantly in the recent decades. Pathophysiological changes associated with …

Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review

AS Alobaid, M Hites, J Lipman, FS Taccone… - International journal of …, 2016 - Elsevier
The increased prevalence of obesity presents challenges for clinicians aiming to provide
optimised antimicrobial dosing in the intensive care unit. Obesity is likely to exacerbate the …

Comprehensive guidance for antibiotic dosing in obese adults

L Meng, E Mui, MK Holubar… - … : The Journal of Human …, 2017 - Wiley Online Library
Physiologic alterations seen in obesity commonly impact the pharmacokinetics (PK) and
pharmacodynamics (PD) of antibiotics and may result in suboptimal dosing in this …

Comprehensive guidance for antibiotic dosing in obese adults.

MLN Meng LiNa, E Mui, MK Holubar, SC Deresinski - 2017 - cabidigitallibrary.org
Physiologic alterations seen in obesity commonly impact the pharmacokinetics (PK) and
pharmacodynamics (PD) of antibiotics and may result in suboptimal dosing in this …

[PDF][PDF] An investigation of the pharmacokinetics of piperacillin, meropenem and fluconazole in critically ill obese patients

A Al-Obaid - 2016 - core.ac.uk
The increasing numbers of critically ill obese patients in the intensive care unit (ICU) and the
high frequency of antimicrobial prescription in these patients present a challenge for …

Updated antimicrobial dosing recommendations for obese patients

A Castro-Balado, I Varela-Rey, B Mejuto… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
The prevalence of obesity has increased considerably in the last few decades.
Pathophysiological changes in obese patients lead to pharmacokinetic (PK) and …