The use of porous three-dimensional (3D) composite scaffolds has attracted great attention
in bone tissue engineering applications because they closely simulate the major features of …

Three-dimensional grafts/scaffolds with hierarchically biomimetic features from nano to
macro scale and high porosity are required for bone tissue engineering. In this study …

Bone tissue engineering is a promising approach for tackling clinical challenges.
Osteoprogenitor cells, osteogenic factors, and osteoinductive/osteoconductive scaffolds are …

Background and Purpose The extracellular matrix (ECM) derived from bone marrow
mesenchymal stem cells (BMSCs) has been used in regenerative medicine because of its …

At present, the treatment of bone defect is one of the most concerned problems in
biomedical fields. Despite the wide variety of scaffolds, there is a challenge to select …

Abstract Engineering three-dimensional (3-D) porous scaffolds with precise bio-functional
properties is one of the most important issues in tissue engineering. In the present study, a …

The 3D-printed hybrid biodegradable hydrogels composed of alginate, gelatin, and
cellulose nanocrystals (CNCs) were prepared to provide a favorable environment for cell …

Polymer-based composite scaffolds are an attractive class of biomaterials due to their
suitable physical and mechanical performance as well as appropriate biological properties …

Background Due to the increasing number of patients with bone defects, bone nonunion and
osteo-myelitis, tumor and congenital diseases, bone repair has become an urgent problem …

In bone tissue engineering, the endogenous regeneration of bone defects still represents a
clinical challenge despite the development of intervention therapy to achieve bone …