Atenolol: a reappraisal of its pharmacological properties and therapeutic use in cardiovascular disorders

AN Wadworth, D Murdoch, RN Brogden - Drugs, 1991 - Springer
Synopsis Atenolol is a selective β 1-adrenoceptor antagonist with a duration of activity of at
least 24 hours. The scope of therapeutic use of the drug has been expanded and become …

Atenolol: a review of its pharmacological properties and therapeutic efficacy in angina pectoris and hypertension

RC Heel, RN Brogden, TM Speight, GS Avery - Drugs, 1979 - Springer
Synopsis: Atenolol 1 is a β 1-selective (cardioselective) adrenoceptor blocking drug without
partial agonist or membrane stabilising activity. Its profile of action most closely resembles …

Acebutolol: a review of its pharmacological properties and therapeutic efficacy in hypertension, angina pectoris and arrhythmia

BN Singh, WR Thoden, A Ward - Drugs, 1985 - Springer
Synopsis: Acebutolol 1 is a cardioselective β-adrenoceptor blocking drug possessing both
partial agonist (intrinsic sympathomimetic) and membrane stabilising activity. In …

Controlled trial of acebutolol in hypertension

L Hansson, G Berglund, O Andersson… - European Journal of …, 1977 - Springer
Acebutolol, a new cardioselective beta-adrenoceptor blocking agent, has been evaluated for
the treatment of hypertension. Thirty eight previously untreated male patients with essential …

Studies on the pharmacokinetics and pharmacodynamics of atenolol in man

JD Fitzgerald, R Ruffin, KG Smedstad… - European journal of …, 1978 - Springer
The non-stimulant cardioselective beta adrenocepter antagonist atenolol has been studied
in volunteers in order to define its pharmacokinetic characteristics. Atenolol (100 and 200 …

Atenolol and three nonselective β‐blockers in hypertension

HJ Waal-Manning - Clinical Pharmacology & Therapeutics, 1979 - Wiley Online Library
The object of this study was to establish whether cardioselectivity of atenolol confers any
advantage over noncardioselective β‐blockade in the treatment of hypertension. A dose of …

Nadolol: a review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris

RC Heel, RN Brogden, GE Pakes, TM Speight… - Drugs, 1980 - Springer
Synopsis: Nadolol 1 is a nonselective β-adrenoceptor blocking drug without intrinsic
sympathomimetic or membrane stabilising activity. Its inherently long duration of activity …

Atenolol once‐daily in hypertension.

TA Jeffers, J Webster, JC Petrie… - British Journal of Clinical …, 1977 - Wiley Online Library
1 The effect of atenolol, a cardioselective beta adrenoceptor antagonist, was studied in a
double‐blind crossover trial in twenty‐one carefully selected hypertensive outpatients. Each …

Long‐Term Clinical Experience with Atenolol—a New Selective β‐1‐Blocker with Few Side‐Effects from the Central Nervous System

NC Henningsen, I Mattiasson - Acta Medica Scandinavica, 1979 - Wiley Online Library
During the last four years we have used a new cardioselective β‐adrenergic blocking
substance, ICI 66.082 (atenolol or Tenormin®), alone or in combination with other drugs for …

Pharmacokinetics of atenolol in patients with renal impairment

J Sassard, N Pozet, J McAinsh, J Legheand… - European Journal of …, 1977 - Springer
The pharmacokinetics of atenolol, a new cardioselective β-adrenoceptor blocking agent,
were determined following both acute and chronic dosing in 33 hypertensive patients with …