Mechanisms of ovarian aging in women: a review

X Wang, L Wang, W Xiang - Journal of Ovarian Research, 2023 - Springer
Ovarian aging is a natural and physiological aging process characterized by loss of quantity
and quality of oocyte or follicular pool. As it is generally accepted that women are born with a …

[HTML][HTML] The molecular regulation in the pathophysiology in ovarian aging

CJ Li, LT Lin, HW Tsai, CU Chern, ZH Wen… - Aging and …, 2021 - ncbi.nlm.nih.gov
The female reproductive system is of great significance to women's health. Aging of the
female reproductive system occurs approximately 10 years prior to the natural age …

Aging conundrum: A perspective for ovarian aging

J Wu, Y Liu, Y Song, L Wang, J Ai, K Li - Frontiers in Endocrinology, 2022 - frontiersin.org
Progressive loss of physiological integrity and accumulation of degenerative changes
leading to functional impairment and increased susceptibility to diseases are the main …

The process of ovarian aging: it is not just about oocytes and granulosa cells

A Camaioni, MA Ucci, L Campagnolo… - Journal of assisted …, 2022 - Springer
Ovarian age is classically considered the main cause of female reproductive infertility. In
women, the process proceeds as an ongoing decline in the primordial follicle stockpile and it …

Ovarian aging: molecular mechanisms and medical management

J Tesarik, M Galán-Lázaro… - International journal of …, 2021 - mdpi.com
This is a short review of the basic molecular mechanisms of ovarian aging, written with a
particular focus on the use of this data to improve the diagnostic and therapeutic protocols …

Current understanding of ovarian aging

Q Li, XD Geng, W Zheng, J Tang, B Xu… - Science China Life …, 2012 - Springer
The reproductive system of human female exhibits a much faster rate of aging than other
body systems. Ovarian aging is thought to be dominated by a gradual decreasing numbers …

[HTML][HTML] Ovarian aging and premature ovarian failure

YE Şükür, İB Kıvançlı, B Özmen - Journal of the Turkish German …, 2014 - ncbi.nlm.nih.gov
Physiological reproductive aging occurs as a result of a decrease in the number and quality
of oocytes in ovarian cortex follicles. Although the reason for the decrease in the quality of …

Oocyte senescence: a firm link to age-related female subfertility

C Tatone - Gynecological Endocrinology, 2008 - Taylor & Francis
In women optimal fertility is maintained until 30 years of age and then decreases sharply.
Therefore, the trend to delay childbearing until the fourth decade of life has contributed …

Oocyte aging: the role of cellular and environmental factors and impact on female fertility

TA Ahmed, SM Ahmed, Z El-Gammal… - Cell Biology and …, 2020 - Springer
Female aging is one of the most important factors that impacts human reproduction. With
aging, there is a natural decline in female fertility. The decrease in fertility is slow and steady …

Ovarian ageing: the role of mitochondria in oocytes and follicles

P May-Panloup, L Boucret… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND There is a great inter-individual variability of ovarian ageing, and almost
20% of patients consulting for infertility show signs of premature ovarian ageing. This …