Neurogenesis occurs in the brain during embryonic development and throughout adulthood.
Neurogenesis occurs in the hippocampus and under normal conditions and persists in two …

Target of rapamycin (TOR) was first identified in yeast as a target molecule of rapamycin, an
anti-fugal and immunosuppressant macrolide compound. In mammals, its orthologue is …

Dysregulation of neural stem cells (NSCs) is associated with several neurodevelopmental
disorders, including epilepsy and autism spectrum disorder. The mammalian target of …

Cancer cells coordinate the mTORC1 signals and the related metabolic pathways to robustly
and rapidly grow in response to nutrient conditions. Although a CNC-family transcription …

In recent years, a significant progress was made in understanding molecular mechanisms of
long-term memory. Long-term memory formation requires strengthening of neuronal …

Mammalian/mechanistic target of rapamycin (mTOR) is a serine-threonine kinase that
controls several important aspects of mammalian cell function. mTOR activity is modulated …

The mammalian Target of Rapamycin (mTOR) is a molecular complex equipped with kinase
activity which controls cell viability being key in the PI3K/PTEN/Akt pathway. mTOR acts by …

Abstract mTOR is a serine/threonine kinase composed of multiple protein components.
Intracellular signaling of mTOR complexes is involved in many of physiological functions …

Neurodegenerative diseases (NDs) cause progressive loss of neurons in nervous system.
NDs are categorized as acute NDs such as stroke and head injury, besides chronic NDs …

The mammalian target of rapamycin (mTOR) pathway is a central controller of growth and
homeostasis, and, as such, is implicated in disease states where growth is deregulated …