[HTML][HTML] Current management and emerging therapies in multiple system atrophy

MR Burns, NR McFarland - Neurotherapeutics, 2020 - Elsevier
Multiple system atrophy (MSA) is a progressive neurodegenerative disease variably
associated with motor, nonmotor, and autonomic symptoms, resulting from putaminal and …

Multiple system atrophy: current and future approaches to management

O Flabeau, WG Meissner… - Therapeutic advances in …, 2010 - journals.sagepub.com
Multiple system atrophy (MSA) is a rare neurodegenerative disorder without any effective
treatment in slowing or stopping disease progression. It is characterized by poor levodopa …

Recent Advances in Clinical Trials in Multiple System Atrophy

D Bendetowicz, M Fabbri, F Sirna, PO Fernagut… - Current Neurology and …, 2024 - Springer
Abstract Purpose of Review This review summarizes previous and ongoing neuroprotection
trials in multiple system atrophy (MSA), a rare and fatal neurodegenerative disease …

Multiple system atrophy: emerging targets for interventional therapies

N Stefanova, GK Wenning - Neuropathology and applied …, 2016 - Wiley Online Library
Multiple system atrophy (MSA) is a fatal orphan neurodegenerative disorder that manifests
with rapidly progressive autonomic and motor dysfunction. The disease is characterized by …

Multiple system atrophy: an update and emerging directions of biomarkers and clinical trials

M Liu, Z Wang, H Shang - Journal of Neurology, 2024 - Springer
Multiple system atrophy is a rare, debilitating, adult-onset neurodegenerative disorder that
manifests clinically as a diverse combination of parkinsonism, cerebellar ataxia, and …

Current symptomatic and disease-modifying treatments in multiple system atrophy

L Mészáros, A Hoffmann, J Wihan… - International journal of …, 2020 - mdpi.com
Multiple system atrophy (MSA) is a rare, severe, and rapidly progressive neurodegenerative
disorder categorized as an atypical parkinsonian syndrome. With a mean life expectancy of …

Disease-modifying therapies for multiple system atrophy: where are we in 2022?

V Sidoroff, P Bower, N Stefanova… - Journal of …, 2022 - content.iospress.com
Multiple system atrophy is a rapidly progressive and fatal neurodegenerative disorder. While
numerous preclinical studies suggested efficacy of potentially disease modifying agents …

Novel therapeutic approaches in multiple system atrophy

JA Palma, H Kaufmann - Clinical Autonomic Research, 2015 - Springer
Multiple system atrophy (MSA) is a sporadic, adult onset, relentlessly progressive
neurodegenerative disease characterized by autonomic abnormalities associated with …

[HTML][HTML] Translational therapies for multiple system atrophy: bottlenecks and future directions

N Stefanova - Autonomic Neuroscience, 2018 - Elsevier
Over the last decade a prominent amount of studies in preclinical transgenic models of
multiple system atrophy (MSA) has been performed. These studies have helped understand …

Multiple system atrophy: recent developments and future perspectives

WG Meissner, PO Fernagut, B Dehay… - Movement …, 2019 - Wiley Online Library
Multiple system atrophy (MSA) is a rare and fatal neurodegenerative disorder characterized
by a variable combination of parkinsonism, cerebellar impairment, and autonomic …