Background: Exposure to certain carcinogens together with host genetic predisposition likely
has an influence on cervical carcinogenesis. Objective: Our aim was to evaluate synergistic …

To evaluate the relationships between genetic polymorphisms of the GSTs (GSTM1 and
GSTT1) and cervicalcancer, the null genotype of each gene was studied in squamous cell …

There were some studies on the associations between Glutathione S-transferase M1
(GSTM1) and Glutathione S-transferase T1 (GSTT1) polymorphisms and cervical cancer …

Purpose Human papillomavirus (HPV) infection is considered the major cause of cervical
cancer (CC), but a number of infected women do not develop invasive lesions, suggesting …

Previous studies have suggested that glutathione S-transferase (GST) genotypes may play a
role in determining susceptibility to cervical cancer, though the data have often been …

Gene deletions in GSTM1 and GSTT1 may result in tempering the activation and
detoxification of several carcinogens and thereby may increase the risk of cancer pre …

Glutathione S-transferases (GSTs) play an important role in detoxification of carcinogenic
electrophiles. The null genotypes in GSTM1 and GSTT1 have been implicated in …

Background Human papillomavirus (HPV) infection is considered the major cause of
cervical cancer (CC), but a number of infected women do not develop invasive lesions …

Introduction: A debate exists about whether glutathione S-transferase (GST) polymorphisms
(GST mu-1 [GSTM1] null/present genotype and GST theta-1 [GSTT1] null/present genotype) …

The factors that determine progression of cervical intraepithelial neoplasia (CIN) to
squamous cell carcinoma (SCC) are unknown. Cigarette smoking is a risk factor, suggesting …