Fast fluorescence lifetime imaging techniques: A review on challenge and development

X Liu, D Lin, W Becker, J Niu, B Yu, L Liu… - Journal of Innovative …, 2019 - World Scientific
Fluorescence lifetime imaging microscopy (FLIM) is increasingly used in biomedicine,
material science, chemistry, and other related research fields, because of its advantages of …

Applications of fluorescence lifetime imaging in clinical medicine

Z Wang, Y Zheng, D Zhao, Z Zhao, L Liu… - Journal of Innovative …, 2018 - World Scientific
Fluorescence lifetime is not only associated with the molecular structure of fluorophores, but
also strongly depends on the environment around them, which allows fluorescence lifetime …

Recent innovations in fluorescence lifetime imaging microscopy for biology and medicine

R Datta, A Gillette, M Stefely… - Journal of Biomedical …, 2021 - spiedigitallibrary.org
Significance: Fluorescence lifetime imaging microscopy (FLIM) measures the decay rate of
fluorophores, thus providing insights into molecular interactions. FLIM is a powerful …

High-speed multispectral fluorescence lifetime imaging implementation for in vivo applications

S Shrestha, BE Applegate, J Park, X Xiao, P Pande… - Optics Letters, 2010 - opg.optica.org
Fluorescence lifetime imaging microscopy (FLIM) offers a noninvasive approach for
characterizing the biochemical composition of biological tissue. In recent years, there has …

Fluorescence lifetime imaging (FLIM): Basic concepts and some recent developments

K Suhling, LM Hirvonen, JA Levitt, PH Chung… - Medical photonics, 2015 - Elsevier
Fluorescence lifetime imaging (FLIM) is a key fluorescence microscopy technique to map the
environment and interaction of fluorescent probes. It can report on photophysical events that …

Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications

R Datta, TM Heaster, JT Sharick… - … of biomedical optics, 2020 - spiedigitallibrary.org
Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …

[HTML][HTML] FLIM as a promising tool for cancer diagnosis and treatment monitoring

Y Ouyang, Y Liu, ZM Wang, Z Liu, M Wu - Nano-Micro Letters, 2021 - Springer
Fluorescence lifetime imaging microscopy (FLIM) has been rapidly developed over the past
30 years and widely applied in biomedical engineering. Recent progress in fluorophore …

Time-domain fluorescence lifetime imaging applied to biological tissue

D Elson, J Requejo-Isidro, I Munro, F Reavell… - Photochemical & …, 2004 - Springer
Fluorescence lifetime imaging (FLIM) is a functional imaging methodology that can provide
information, not only concerning the localisation of specific fluorophores, but also about the …

Biomedical applications of fluorescence lifetime imaging

D Elson, S Webb, J Siegel, K Suhling… - Optics and photonics …, 2002 - opg.optica.org
Biomedical Applications of Fluorescence Lifetime Imaging Page 1 Dan Elson, Stephen
Webb, Jan Siegel, Klaus Suhling, Dan Davis, John Lever, David Phillips, Andrew Wallace …

A novel fluorescence lifetime imaging system that optimizes photon efficiency

RA Colyer, C Lee, E Gratton - Microscopy research and …, 2008 - Wiley Online Library
Fluorescence lifetime imaging (FLIM) is a powerful microscopy technique for providing
contrast of biological and other systems by differences in molecular species or their …