PET reporter systems for the brain

SG Nerella, M Michaelides, T Minamimoto… - Trends in …, 2023 - cell.com
Positron emission tomography (PET) can be used as a noninvasive method to longitudinally
monitor and quantify the expression of proteins in the brain in vivo. It can be used to monitor …

Human positron emission tomography neuroimaging

JM Hooker, RE Carson - Annual review of biomedical …, 2019 - annualreviews.org
Neuroimaging with positron emission tomography (PET) is the most powerful tool for
understanding pharmacology, neurochemistry, and pathology in the living human brain. This …

Approaches for the discovery of novel positron emission tomography radiotracers for brain imaging

A Need, N Kant, C Jesudason, V Barth - Clinical and Translational …, 2017 - Springer
Purpose Positron emission tomography (PET) is a widely used imaging technique with many
biomedical and drug development applications. The implementation of this technology …

PET-based molecular imaging in neuroscience

AH Jacobs, H Li, A Winkeler, R Hilker, C Knoess… - European journal of …, 2003 - Springer
Positron emission tomography (PET) allows non-invasive assessment of physiological,
metabolic and molecular processes in humans and animals in vivo. Advances in detector …

Molecular imaging of biological processes with PET: evaluating biologic bases of cerebral function

ME Phelps, DHS Silverman, WP Melega - PET: Molecular Imaging and Its …, 2004 - Springer
Neuroimaging studies with positron emission tomography (PET) have advanced our
understanding of the human brain by noninvasively assessing several aspects of cerebral …

Quantitative rodent brain receptor imaging

K Herfert, JG Mannheim, L Kuebler, S Marciano… - Molecular Imaging and …, 2020 - Springer
Positron emission tomography (PET) is a non-invasive imaging technology employed to
describe metabolic, physiological, and biochemical processes in vivo. These include …

New imaging technologies to enhance the molecular sensitivity of positron emission tomography

CS Levin - Proceedings of the IEEE, 2008 - ieeexplore.ieee.org
Positron emission tomography (PET) is used in the clinic and in vivo small animal research
to study certain molecular processes associated with diseases such as cancer, heart …

PET applications in animal models of neurodegenerative and neuroinflammatory disorders

M Higuchi, J Maeda, B Ji, M Tokunaga… - Brain Imaging in …, 2012 - Springer
Studies on hereditary neurological disorders such as familial Alzheimer's disease (AD) have
revealed abnormalities of pathogenic proteins causative of neurodegeneration, while …

Molecular medicine successes in neuroscience

B Schaller, JF Cornelius, N Sandu - Molecular Medicine, 2008 - Springer
In this issue of Molecular Medicine, Irvine et al.(1) expound upon the application of
molecular biology in clinical medicine and the enabling of targeted interactions at a …

The application of positron emission tomography (PET) imaging in CNS drug development

I Suridjan, RA Comley, EA Rabiner - Brain imaging and behavior, 2019 - Springer
As drug discovery and development in Neuroscience push beyond symptom management
to disease modification, neuroimaging becomes a key area of translational research that …