An activatable fluorescent-photoacoustic dual-modal probe for highly sensitive imaging of nitroxyl in vivo

FY Qi, L Qiao, L Peng, Y Yang, CH Zhang, X Liu - Analyst, 2024 - pubs.rsc.org
Nitroxyl (HNO) plays a vital role in various biological functions and pharmacological
activities, so the development of an excellent near-infrared fluorescent (NIRF) and …

A robust ratiometric photoacoustic and fluorescence dual-modal molecular probe for capturing endogenous HNO generation in tumor mice model

L Liu, L Wang, B Tan, X Wu, XC Shen… - Sensors and Actuators B …, 2023 - Elsevier
HNO is reported in association with a wide variety of physiological and pathological states.
However, photoacoustic (PA)/fluorescence (FL) dual-modal probes with complementary …

A near-infrared fluorescent probe with ultra-large Stokes shift for the detection of HNO in cells and mice

C Zhang, M Qian, L Zhang, H Zheng, M Zhang… - Journal of …, 2022 - Elsevier
As one of the significant reactive nitrogen species in living systems, nitroxyl (HNO) plays a
paramount role in a series of physiological and pathological processes. However …

Ratiometric photoacoustic imaging of endogenous HNO in vivo for assessing prodrug release and liver injury

X Fan, H Wang, W Yang, T Ren, L Yuan - Chemical Communications, 2023 - pubs.rsc.org
The effective imaging of endogenous HNO is highly crucial for pathology research and
medical development due to its important pharmacological activity in biological systems …

A ratiometric near-infrared fluorescence/photoacoustic dual-modal probe with strong donor dithienopyrrole for in vivo nitric oxide detection

P Xiao, M Liang, S Yang, Y Sun, J Li, Z Gu, Q Fan… - Biomaterials, 2023 - Elsevier
Integrating the imaging techniques of near-infrared fluorescence (NIRF) and photoacoustic
(PA) can make up for each other and provide more useful medical information. Ratiometric …

A novel NIR fluorescent probe for the highly sensitive detection of HNO and its application in bioimaging

S He, J Zhu, P Xie, J Liu, D Zhang, J Tang… - New Journal of …, 2021 - pubs.rsc.org
Nitroxyl (HNO) is an important reactive nitrogen species (RNS), which plays an important
role in multiple physiological processes. Therefore, it is urgent to exploit reliable and efficient …

An isophorone-fused near-infrared fluorescent probe with a large Stokes shift for imaging endogenous nitroxyl in living cells and zebrafish

C Wei, X Wang, X Li, X Jia, X Hao, J Zhang… - … Acta Part A: Molecular …, 2020 - Elsevier
Nitroxyl (HNO) plays an important role in multiple physiological and pathological processes,
but the detailed generation mechanism of the endogenous HNO still remained to explore …

A Tumor-Targeting Dual-Modal imaging probe for nitroreductase in vivo

T Li, ZC Yang, ZQ Wang, ZZ Peng, GJ Mao… - Bioorganic …, 2024 - Elsevier
Nitroreductase (NTR) overexpression often occurs in tumors, highlighting the significance of
effective NTR detection. Despite the utilization of various optical methods for this purpose …

A dual-modal molecular probe for near-infrared fluorescence and photoacoustic imaging of peroxynitrite

J Zhang, X Zhen, J Zeng, K Pu - Analytical chemistry, 2018 - ACS Publications
Peroxynitrite (ONOO–), a reactive and short-lived biological oxidant, is closely related with
many pathological conditions such as cancer. However, real-time in vivo imaging of ONOO …

In vivo near-infrared fluorescence/ratiometric photoacoustic duplex imaging of lung cancer-specific hNQO1

X Zhang, K Jiang, S Jiang, F Zhao, P Chen… - Analytical …, 2022 - ACS Publications
Overexpressing human NAD (P) H: quinone oxidoreductase 1 (hNQO1) in lung cancer
tissues is deemed to be an attractive biomarker, which is directly connected to cancerous …