Inflammatory bowel disease (IBD) patients have an increased risk of developing colitis-
associated colon cancer (CAC); however, the basis for inflammation-induced genetic …

One of the contributory causes of colon cancer is the negative effect of reactive oxygen
species on DNA repair mechanisms. Currently, there is a growing support for the concept …

This review focuses on the roles antioxidants and pro-oxidants in colorectal cancer (CRC).
Considerable evidence suggests that environmental factors play key roles in the incidence …

The chronic inflammatory bowel disease ulcerative colitis (UC) occurs commonly in the US
and other Western countries, but its etiology is unknown. An association between UC and an …

Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …

Ulcerative colitis is an idiopathic, chronic and relapsing inflammatory bowel disease, which
elicits the risk of colorectal cancer, the third most common malignancy in humans. It has …

Inflammatory bowel disease (IBD) belongs to a group of chronic diseases characterised by
periods of exacerbation and remission. Despite many studies and observations, its …

The global incidence of inflammatory bowel disease (IBD), a group of chronic
gastrointestinal disorders, has been rising. The preponderance of evidence demonstrates …

This review will focus on published human studies on oxidative stress and DNA damage in
inflammatory bowel disease (IBD), both ulcerative colitis and Crohn's disease, assessing …

There is a growing support for the concept that reactive oxygen species, which are known to
be implicated in a range of diseases, may be important progenitors in carcinogenesis …