The kinesin, dynein, and myosin superfamily molecular motors have fundamental roles in
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …

Molecular motors such as kinesin superfamily proteins (KIFs), dynein superfamily proteins
and myosin superfamily proteins have diverse and fundamental roles in many cellular …

Kinesin and dynein molecular motor proteins generate the movement of a wide variety of
materials in cells. Such movements are crucial for many different cellular and developmental …

Intracellular transport is fundamental for neuronal morphogenesis, function and survival.
Many proteins are selectively transported to either axons or dendrites. In addition, some …

Eukaryotic cells organize their cytoplasm by moving different organelles and
macromolecular complexes along microtubules and actin filaments. These movements are …

Many eukaryotic cells distribute their intracellular components asymmetrically through
regulated active transport driven by molecular motors along microtubule tracks. While …

The large size and extreme polarization of neurons is crucial to their ability to communicate
at long distances and to form the complex cellular networks of the nervous system. The size …

Within axons vital cargoes must be transported over great distances along microtubule
tracks to maintain neuronal viability. Essential to this system are the molecular motors …

Axonal transport is indispensable for the distribution of vesicles, organelles, messenger
RNAs (mRNAs), and signaling molecules along the axon. This process is mediated by …

The active transport of organelles and other cargos along the axon is required to maintain
neuronal health and function, but we are just beginning to understand the complex …