3.1 Leukemia Acute leukemia is a clonal malignancy of the hematopoietic system that is
characterized by loss of cell differentiation and uncontrolled proliferation of …

Acute myeloid leukemia (AML) is the most common acute leukemia in the adult population. It
is characterized by the high proliferation of undifferentiated hematopoietic cells, which …

Acute myeloid leukemia (AML) is a highly heterogeneous malignancy of the blood and bone
marrow, characterized by clonal expansion of myeloid stem and progenitor cells and rapid …

Background Chronic lymphocytic leukemia (CLL) is a heterogenous B cell malignancy that
is the most common adult leukemia in Western countries (1, 2). CLL cell survival depends on …

Simple Summary Acute myeloid leukemia (AML) is a cancer characterized by impaired
differentiation and excessive expansion of blood progenitor cells leading to their …

1 Background Acute leukemia is a clonal hematopoietic cancer originating in the bone
marrow (BM) and can be classified into two types: acute lymphoid leukemia (ALL) and acute …

Acute myeloid leukemia (AML) is a molecularly and clinically heterogeneous hematologic
malignancy that progresses rapidly and originates from a rare population of leukemic stem …

Despite the results achieved with the evolution of conventional chemotherapy and the
inclusion of targeted therapies in the treatment of acute myeloid leukemia (AML), survival is …

Acute myeloid leukemia (AML) patients rarely have long first remissions (> 5 years) after
standard-of-care chemotherapy, unless classified as favorable risk at presentation …

The contribution of the leukaemic microenvironment (LME) for acute myeloid leukaemia
(AML) development and maintenance is gaining much and increasing interest. A better …