Drug repositioning in chemoprevention of colorectal cancer

N Zhang - 2023 - portal.research.lu.se
Background Colorectal cancer (CRC) ranks as the third most frequently occurring cancer
and the second leading cause of cancer-related deaths worldwide. In response to the high …

Colorectal cancer chemoprevention: a dream coming true?

M Lepore Signorile, V Grossi, C Fasano… - International Journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the deadliest forms of cancer worldwide. CRC
development occurs mainly through the adenoma-carcinoma sequence, which can last …

Colorectal cancer chemoprevention: Ready for practice?

S Kraus, N Arber - European Journal of Cancer, 2009 - Elsevier
At the dawn of this century, cancer prevention is the new frontier for cancer therapy. This is
especially significant because cancer is predicted to become the leading cause of death …

Chemoprevention of colorectal cancer: ready for routine use?

N Arber, B Levin - Current Topics in Medicinal Chemistry, 2005 - ingentaconnect.com
In the third millennium preventive medicine is becoming a corner stone in our concept of
health. Colorectal cancer (CRC) prevention, in particular, has become an important goal for …

Molecular targets in precision chemoprevention of colorectal cancer: an update from pre-clinical to clinical trials

NS Yarla, V Madka, G Pathuri, CV Rao - International Journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is one of the leading causes of cancer deaths worldwide. The
initiation and progression of CRC is a multi-step process that proceeds via precursor lesions …

[引用][C] Colorectal cancer chemoprevention

PJ Limburg, JC Kolars - Chinese Journal of Digestive Diseases, 2004 - Wiley Online Library
Colorectal cancer (CRC) is an emerging public health problem in the Peoples' Republic of
China. In Shanghai, the incidence of CRC increased approximately 100% between 1972 …

[HTML][HTML] Preventive effects of 13 different drugs on colorectal cancer: a network meta-analysis

Q Fu, H Liao, Z Li, X Chen, X Zhang… - Archives of medical …, 2023 - ncbi.nlm.nih.gov
Results A total of 57 studies (34 RCTs and 23 cohort studies) involving 82719 participants
were included. The network meta-analysis revealed that the quality of the included studies …

[HTML][HTML] Systems-level biomarkers identification and drug repositioning in colorectal cancer

H Beklen, E Yildirim, M Kori, B Turanli… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the most commonly diagnosed fatal cancer in both women and
men worldwide. CRC ranked second in mortality and third in incidence in 2020. It is difficult …

[HTML][HTML] Cancer chemoprevention: Much has been done, but there is still much to do. State of the art and possible new approaches

D Serrano, M Lazzeroni, B Bonanni - Molecular Oncology, 2015 - Elsevier
Over the past three decades great efforts have been made in search of cancer
chemoprevention strategies. The increase in knowledge of the long process from normal to …

[HTML][HTML] Comparative effectiveness of chemopreventive interventions for colorectal cancer: protocol for a systematic review and network meta-analysis of randomised …

SK Veettil, S Saokaew, KG Lim, SM Ching… - Journal of …, 2016 - ncbi.nlm.nih.gov
Background Colorectal cancer (CRC) is the third most common cancer worldwide and is
associated with substantial socioeconomic burden. Despite considerable research …