Titanium dioxide nanoparticles prime a specific activation state of macrophages

C Huang, M Sun, Y Yang, F Wang, X Ma, J Li… - …, 2017 - Taylor & Francis
Abstract Titanium dioxide nanoparticles (TiO2 NPs) are widely used in foods, cosmetics, and
medicine. Although the inhalation toxicity of TiO2 NPs has been studied, the potential …

Titanium dioxide nanoparticles enhance macrophage activation by LPS through a TLR4-dependent intracellular pathway

MG Bianchi, M Allegri, AL Costa, M Blosi… - Toxicology …, 2015 - academic.oup.com
Although causing moderate cytotoxicity and inflammatory effects, TiO2 nanoparticles (NPs)
are considered relatively safe materials. However, it is known that TiO2 NPs bind bioactive …

[HTML][HTML] Titanium dioxide nanoparticles modulate systemic immune response and increase levels of reduced glutathione in mice after seven-week inhalation

M Lehotska Mikusova, M Busova, J Tulinska… - Nanomaterials, 2023 - mdpi.com
Titanium dioxide nanoparticles (TiO2 NPs) are used in a wide range of applications.
Although inhalation of NPs is one of the most important toxicologically relevant routes …

Small-sized titanium dioxide nanoparticles mediate immune toxicity in rat pulmonary alveolar macrophages in vivo

R Liu, X Zhang, Y Pu, L Yin, Y Li… - … of nanoscience and …, 2010 - ingentaconnect.com
Small-sized titanium dioxide (TiO2 nanoparticles (2 nanoparticles on the immune function of
rat pulmonary alveolar macrophages in vivo. Forty-two rats were intra-tracheally instilled …

Lung exposure of titanium dioxide nanoparticles induces innate immune activation and long-lasting lymphocyte response in the Dark Agouti rat

Å Gustafsson, E Lindstedt, LS Elfsmark… - Journal of …, 2011 - Taylor & Francis
Nanomaterial of titanium dioxide (TiO2) is manufactured in large-scale production plants,
resulting in risks for accidental high exposures of humans. Inhalation of metal oxide …

Airway Exposure to Silica-Coated TiO2 Nanoparticles Induces Pulmonary Neutrophilia in Mice

EM Rossi, L Pylkkänen, AJ Koivisto… - Toxicological …, 2010 - academic.oup.com
The importance of nanotechnologies and engineered nanoparticles has grown rapidly. It is
therefore crucial to acquire up-to-date knowledge of the possible harmful health effects of …

Route-dependent systemic and local immune effects following exposure to solutions prepared from titanium dioxide nanoparticles

W Auttachoat, CE McLoughlin, KL White Jr… - Journal of …, 2014 - Taylor & Francis
Nanoparticle titanium dioxide (nano-TiO2) is a white pigment widely used in foods,
sunscreens, and other cosmetic products. However, it remains unclear whether exposure to …

The immune toxicity of titanium dioxide on primary pulmonary alveolar macrophages relies on their surface area and crystal structure

R Liu, L Yin, Y Pu, Y Li, X Zhang… - … of nanoscience and …, 2010 - ingentaconnect.com
Surface properties are critical to assess effects of titanium dioxide (TiO2) primary
nanoparticles on the immune function of pulmonary alveolar macrophage (PAMs). In this …

Titanium dioxide nanoparticles exacerbate pneumonia in respiratory syncytial virus (RSV)-infected mice

S Hashiguchi, H Yoshida, T Akashi… - Environmental …, 2015 - Elsevier
To reveal the effects of TiO 2 nanoparticles, used in cosmetics and building materials, on the
immune response, a respiratory syncytial virus (RSV) infection mouse model was used …

Cytotoxic and inflammatory responses of TiO2 nanoparticles on human peripheral blood mononuclear cells

S Kongseng, K Yoovathaworn… - Journal of Applied …, 2016 - Wiley Online Library
Abstract Titanium dioxide nanoparticles (TiO2‐NPs) have been widely used in many
applications. Owing to their nanoscale size, interactions between cells and NPs have been …