[HTML][HTML] The diagnostic potential and barriers of microbiome based therapeutics

A Acharjee, U Singh, SP Choudhury, GV Gkoutos - Diagnosis, 2022 - degruyter.com
High throughput technological innovations in the past decade have accelerated research
into the trillions of commensal microbes in the gut. The 'omics' technologies used for …

[HTML][HTML] Gut Microbiome and Disorders of the Gastrointestinal Tract

A Hammerhøj, JM Gubatan, OH Nielsen - Microorganisms, 2024 - mdpi.com
The protective intestinal epithelial barrier is constantly exposed to more than 100 trillion
commensal microorganisms (bacteria, archaea, viruses, and fungi), ie, the microbiome …

Understanding microbiome data: a primer for clinicians

P Seksik, C Landman - Digestive Diseases, 2015 - karger.com
The human gut contains 10 14 bacteria and many other micro-organisms such as Archaea,
viruses and fungi. This gut microbiota has co-evolved with host determinants through …

Emerging science of the human microbiome

ML Jones, JG Ganopolsky, CJ Martoni, A Labbé… - Gut …, 2014 - Taylor & Francis
The human gastrointestinal tract hosts a large number of microbial cells which exceed their
mammalian counterparts by approximately 3-fold. The genes expressed by these …

[HTML][HTML] Explainable artificial intelligence for microbiome data analysis in colorectal cancer biomarker identification

P Novielli, D Romano, M Magarelli, PD Bitonto… - Frontiers in …, 2024 - frontiersin.org
Background Colorectal cancer (CRC) is a type of tumor caused by the uncontrolled growth
of cells in the mucosa lining the last part of the intestine. Emerging evidence underscores an …

Next steps after 15 stimulating years of human gut microbiome research

T Clavel, HP Horz, N Segata… - Microbial …, 2022 - Wiley Online Library
Gut microbiome research has bloomed over the past 15 years. We have learnt a lot about
the complex microbial communities that colonize our intestine. Promising avenues of …

Navigating the human gut microbiome: pathway to success from lessons learned

J Miyoshi, MC Rao, EB Chang - Gastroenterology, 2020 - gastrojournal.org
The rapid evolu-tion of cultivationindependent, multi-omic technologies has increased our
appreciation of the complexity, diversity, and vital roles of the human gut microbiome in …

Current capabilities of gut microbiome–based diagnostics and the promise of clinical application

GL Damhorst, MW Adelman… - The Journal of …, 2021 - academic.oup.com
There is increasing evidence for the importance of the gut microbiome in human health and
disease. Traditional and modern technologies-from cell culture to next generation …

Resources and tools for the high-throughput, multi-omic study of intestinal microbiota

A Blanco-Míguez, F Fdez-Riverola… - Briefings in …, 2019 - academic.oup.com
The human gut microbiome impacts several aspects of human health and disease, including
digestion, drug metabolism and the propensity to develop various inflammatory …

Our microbiome: On the challenges, promises, and hype

S Federici, J Suez, E Elinav - Symbiosis: Cellular, molecular, medical and …, 2020 - Springer
The microbiome field is increasingly raising interest among scientists, clinicians,
biopharmaceutical entities, and the general public. Technological advances from the past …