Emerging data from several studies regarding PRS in PCa could be the solution to adding
predictive value to PCa risk estimation. Although commercial markers are available …

Background Genome‐wide association studies have identified over 100 single‐nucleotide
polymorphisms (SNPs) associated with prostate cancer (PrCa), and polygenic risk scores …

Polygenic risk scores for prostate cancer: testing considerations Page 1 © The Canadian
Journal of UrologyTM: International Supplement, October 2019 Polygenic risk scores for …

Background and objective Polygenic risk scores (PRSs) have been developed to identify
men with the highest risk of prostate cancer. Our aim was to compare the performance of 16 …

Objectives Genome-wide association studies have revealed over 200 genetic susceptibility
loci for prostate cancer (PCa). By combining them, polygenic risk scores (PRS) can be …

Decreasing costs of genetic testing and interest in disease inheritance has changed the
landscape of cancer prediction in prostate cancer (PCa), and guidelines now include …

BACKGROUND: More than 1 million prostate biopsies are conducted yearly in the United
States. The low specificity of prostate-specific antigen (PSA) results in diagnostic biopsies in …

Aims The purpose of this study is to evaluate an aggregate influence of prostate cancer
(PCa) susceptibility variants on the development of PCa in Korean men by using the …

Recent advances in our understanding of genetic factors that contribute to prostate cancer
(PCa) susceptibility have the potential to improve disease screening, diagnosis, and …

Purpose To develop and evaluate the performance of a polygenic risk score (PRS)
constructed in a Korean male population to predict clinically significant prostate cancer …