Autophagy in tumour immunity and therapy
Autophagy is a regulated mechanism that removes unnecessary or dysfunctional cellular
components and recycles metabolic substrates. In response to stress signals in the tumour …
components and recycles metabolic substrates. In response to stress signals in the tumour …
Autophagy, the innate immune response and cancer
C Gerada, KM Ryan - Molecular oncology, 2020 - Wiley Online Library
Autophagy is a cellular degradation and recycling system, which can interact with
components of innate immune signalling pathways to enhance pathogen clearance, in both …
components of innate immune signalling pathways to enhance pathogen clearance, in both …
[HTML][HTML] Autophagy in cancer immunotherapy
Y Lei, E Zhang, L Bai, Y Li - Cells, 2022 - mdpi.com
Autophagy is a stress-induced process that eliminates damaged organelles and
dysfunctional cargos in cytoplasm, including unfolded proteins. Autophagy is involved in …
dysfunctional cargos in cytoplasm, including unfolded proteins. Autophagy is involved in …
[HTML][HTML] Autophagy-associated immune responses and cancer immunotherapy
H Pan, L Chen, Y Xu, W Han, F Lou, W Fei, S Liu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Autophagy is an evolutionarily conserved catabolic process by which cellular components
are sequestered into a double-membrane vesicle and delivered to the lysosome for terminal …
are sequestered into a double-membrane vesicle and delivered to the lysosome for terminal …
[HTML][HTML] The role of autophagy in tumor immunology—complex mechanisms that may be explored therapeutically
ASC De Souza, LB Gonçalves, AP Lepique… - Frontiers in …, 2020 - frontiersin.org
The tumor microenvironment (TME) is complex, and its composition and dynamics
determine tumor fate. From tumor cells themselves, with their capacity for unlimited …
determine tumor fate. From tumor cells themselves, with their capacity for unlimited …
[HTML][HTML] Targeting autophagy in the tumor microenvironment: new challenges and opportunities for regulating tumor immunity
Cancer cells evolve in the tumor microenvironment, which is now well established as an
integral part of the tumor and a determinant player in cancer cell adaptation and resistance …
integral part of the tumor and a determinant player in cancer cell adaptation and resistance …
Autophagy in natural and therapy-driven anticancer immunosurveillance
Autophagy is primordial for the maintenance of metabolic and genetic homeostasis in all
eukaryotic organisms. Owing to its cell-intrinsic effects, autophagy robustly inhibits malignant …
eukaryotic organisms. Owing to its cell-intrinsic effects, autophagy robustly inhibits malignant …
[HTML][HTML] Autophagy, inflammation, and immunity: a troika governing cancer and its treatment
Autophagy, a cellular waste disposal process, has well-established tumor-suppressive
properties. New studies indicate that, in addition to its cell-autonomous anti-tumorigenic …
properties. New studies indicate that, in addition to its cell-autonomous anti-tumorigenic …
[HTML][HTML] The relationship between autophagy and the immune system and its applications for tumor immunotherapy
GM Jiang, Y Tan, H Wang, L Peng, HT Chen, XJ Meng… - Molecular cancer, 2019 - Springer
Autophagy is a genetically well-controlled cellular process that is tightly controlled by a set of
core genes, including the family of autophagy-related genes (ATG). Autophagy is a “double …
core genes, including the family of autophagy-related genes (ATG). Autophagy is a “double …
[HTML][HTML] Role of hypoxia-mediated autophagy in tumor cell death and survival
RF Zaarour, B Azakir, EY Hajam, H Nawafleh… - Cancers, 2021 - mdpi.com
Simple Summary Autophagy is a self-eating mechanism that is involved in the degradation
of organelles and cellular materials. It is initiated by intracellular and extracellular stress …
of organelles and cellular materials. It is initiated by intracellular and extracellular stress …