[HTML][HTML] Molecular mechanisms underlying cardiac adaptation to exercise

RB Vega, JP Konhilas, DP Kelly, LA Leinwand - Cell metabolism, 2017 - cell.com
Exercise elicits coordinated multi-organ responses including skeletal muscle, vasculature,
heart, and lung. In the short term, the output of the heart increases to meet the demand of …

Cardiac adaptation to exercise training in health and disease

DY Seo, HB Kwak, AH Kim, SH Park, JW Heo… - … -European Journal of …, 2020 - Springer
The heart is the primary pump that circulates blood through the entire cardiovascular system,
serving many important functions in the body. Exercise training provides favorable …

[HTML][HTML] Metabolic mechanisms of exercise-induced cardiac remodeling

K Fulghum, BG Hill - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Exercise has a myriad of physiological benefits that derive in part from its ability to improve
cardiometabolic health. The periodic metabolic stress imposed by regular exercise appears …

Understanding key mechanisms of exercise-induced cardiac protection to mitigate disease: current knowledge and emerging concepts

BC Bernardo, JYY Ooi, KL Weeks… - Physiological …, 2018 - journals.physiology.org
The benefits of exercise on the heart are well recognized, and clinical studies have
demonstrated that exercise is an intervention that can improve cardiac function in heart …

Exercise and cardiac health: physiological and molecular insights

JBN Moreira, M Wohlwend, U Wisløff - Nature Metabolism, 2020 - nature.com
The cardiac benefits of exercise have been recognized for centuries. Studies have
undisputedly shown that regular exercise is beneficial for the cardiovascular system in …

Molecular pathways underlying cardiac remodeling during pathophysiological stimulation

I Kehat, JD Molkentin - Circulation, 2010 - Am Heart Assoc
Cardiac remodeling involves molecular, cellular, and in-terstitial changes that manifest
clinically as changes in size, shape, and function of the heart after injury or stress …

The IGF1-PI3K-Akt signaling pathway in mediating exercise-induced cardiac hypertrophy and protection

KL Weeks, BC Bernardo, JYY Ooi, NL Patterson… - … disease prevention and …, 2017 - Springer
Regular physical activity or exercise training can lead to heart enlargement known as
cardiac hypertrophy. Cardiac hypertrophy is broadly defined as an increase in heart mass. In …

[HTML][HTML] Exercise for the heart: signaling pathways

L Tao, Y Bei, H Zhang, J Xiao, X Li - Oncotarget, 2015 - ncbi.nlm.nih.gov
Physical exercise, a potent functional intervention in protecting against cardiovascular
diseases, is a hot topic in recent years. Exercise has been shown to reduce cardiac risk …

Protective effects of exercise and phosphoinositide 3-kinase (p110α) signaling in dilated and hypertrophic cardiomyopathy

JR McMullen, F Amirahmadi… - Proceedings of the …, 2007 - National Acad Sciences
Physical activity protects against cardiovascular disease, and physiological cardiac
hypertrophy associated with regular exercise is usually beneficial, in marked contrast to …

[HTML][HTML] Molecular mechanisms of cardiac remodeling and regeneration in physical exercise

D Schüttler, S Clauss, LT Weckbach, S Brunner - Cells, 2019 - mdpi.com
Regular physical activity with aerobic and muscle-strengthening training protects against the
occurrence and progression of cardiovascular disease and can improve cardiac function in …