Mesenchymal Stromal Cell-Derived Extracellular Vesicles Regulate the Mitochondrial Metabolism via Transfer of miRNAs
C Loussouarn, YM Pers, C Bony, C Jorgensen… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are the most commonly tested adult progenitor cells in
regenerative medicine. They stimulate tissue repair primarily through the secretion of …
regenerative medicine. They stimulate tissue repair primarily through the secretion of …
Mesenchymal stem cell-derived extracellular vesicles affect disease outcomes via transfer of microRNAs
G Qiu, G Zheng, M Ge, J Wang, R Huang… - Stem Cell Research & …, 2018 - Springer
Mesenchymal stem cells (MSCs) are adult stromal cells with the capacity to differentiate into
multiple types of cells. MSCs represent an attractive option in regenerative medicine due to …
multiple types of cells. MSCs represent an attractive option in regenerative medicine due to …
Interferon-γ and hypoxia priming have limited effect on the miRNA landscape of human mesenchymal stromal cells-derived extracellular vesicles
Mesenchymal stromal cell (MSC)-based cell therapy has received great interest in
regenerative medicine. Priming the cells during the culture phase can improve their efficacy …
regenerative medicine. Priming the cells during the culture phase can improve their efficacy …
Mesenchymal stem cell-derived extracellular vesicles attenuate mitochondrial damage and inflammation by stabilizing mitochondrial DNA
M Zhao, S Liu, C Wang, Y Wang, M Wan, F Liu… - ACS …, 2020 - ACS Publications
Mitochondrial dysfunction is a key feature of injury to numerous tissues and stem cell aging.
Although the tissue regenerative role of mesenchymal stem cell (MSC)-derived extracellular …
Although the tissue regenerative role of mesenchymal stem cell (MSC)-derived extracellular …
Mesenchymal stem cell-derived extracellular vesicles: toward cell-free therapeutic applications
Mesenchymal stem (stromal) cells (MSCs) are multipotent cells with the ability to differentiate
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …
Human mesenchymal stromal cells release functional mitochondria in extracellular vesicles
MA Thomas, MJ Fahey, BR Pugliese… - … in Bioengineering and …, 2022 - frontiersin.org
Cartilage and other skeletal soft tissues heal poorly after injury, in part due to their lack of
vascularity and low metabolic rate. No pharmacologic approaches have proven effective in …
vascularity and low metabolic rate. No pharmacologic approaches have proven effective in …
Therapeutic effects of mesenchymal stromal cells require mitochondrial transfer and quality control
AN Mukkala, M Jerkic, Z Khan, K Szaszi… - International Journal of …, 2023 - mdpi.com
Due to their beneficial effects in an array of diseases, Mesenchymal Stromal Cells (MSCs)
have been the focus of intense preclinical research and clinical implementation for decades …
have been the focus of intense preclinical research and clinical implementation for decades …
Mesenchymal stem cell-derived extracellular vesicles in tissue regeneration
B Zhang, X Tian, J Hao, G Xu… - Cell transplantation, 2020 - journals.sagepub.com
Mesenchymal stem cells (MSCs) are multipotent stem cells that have attracted increasing
interest in the field of regenerative medicine. Previously, the differentiation ability of MSCs …
interest in the field of regenerative medicine. Previously, the differentiation ability of MSCs …
Extracellular vesicles from stem and progenitor cells for cell-free regenerative therapy
Cell-based regenerative therapies involving stem or progenitor cells are considered as
possible therapeutic modalities to treat non-communicable and degenerative diseases …
possible therapeutic modalities to treat non-communicable and degenerative diseases …
Mesenchymal stem cell (MSC)‐derived extracellular vesicles: potential therapeutics as MSC trophic mediators in regenerative medicine
Q Yuan, Y Zhang, Q Chen - The Anatomical Record, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) are pluripotent progenitor cells with the capabilities of self‐
renewing, differentiating into multiple lineages, and achieving trophic effects during tissue …
renewing, differentiating into multiple lineages, and achieving trophic effects during tissue …
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